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> HSP110 Antibody (FITC)

HSP110 Antibody (FITC)

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Référence orb152135-100ug

Conditionnement : 100ug

Marque : Biorbyt

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HSP110 Antibody (FITC)

SKU: orb152135
This product can be custom made

Description

Rabbit polyclonal to Hsp110 (FITC). Hsp110 belongs to a family of large stress proteins known as the Hsp110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied Hsp70 family. They share 30-33% amino acid identity, mostly in the conserved ATP-binding domain. Hsp110 cooperates with Hsp70 in protein folding in the eukaryotic cytosol. In mammals, Hsp110 is constitutively expressed, but exhibits particularly high levels in the brain. Both Hsp70 and Hsp110 are elevated after cerebral ischemia. Recent studies demonstrate that the protective effects of Hsp110 deficiency in cerebral ischemia may partly be mediated by an increase in the chaperone activity of Hsp70. Studies also suggest that Hsp110 can be used in heat shock protein-based cancer immunotherapy..

Research Area

Cancer Biology, Cell Biology, Protein Biochemistry, Signal Transduction

Images & Validation

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Tested ApplicationsICC, IF, IHC, WB
Dilution RangeWB (1:1000), IHC (1:100)
ReactivityBovine, Fish, Hamster, Human, Monkey, Mouse, Rat, Sheep, Yeast
Application Notes
1 µg/ml was sufficient for detection of HSP110 in 10 µg of human cell line mixed lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Key Properties

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HostRabbit
ClonalityPolyclonal
ImmunogenSynthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse
TargetHSP110
Molecular Weight110kDa
PurificationProtein A Purified
ConjugationFITC

Storage & Handling

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StorageConjugated antibodies should be stored according to the product label
Buffer/Preservatives640.91mM DMSO, 136.36 mM Ethanolamine, 126.89 mM chlorides, 9.09mM phosphates, 9.09mM NaHCO3
Concentration1 mg/ml
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

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HSPH1, HSP110, HSP105, Heat shock protein 105 kDa, Heat shock 110 kDa protein, KIAA0201, Heat shock 105kDa alpha, heat shock 105kDa beta, HSP105A, HSP105B, NY CO 25
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Quick Database Links

Gene Symbol
HSP110
UniProt
Q92599
NCBI Gene ID
10808
RefSeq (Protein):NP_006635.3

UniProt Details

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No UniProt data available

NCBI Gene Details

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Failed to load NCBI Gene data

NCBI Reference Sequences

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Associated Accession Numbers
Curated reference sequences for the gene transcript and protein product
ProteinNP_006635.3

Protocol Information

WB
Western Blot (IB, immunoblot)
View Protocol
IHC
Immunohistochemistry
View Protocol
IF
Immunofluorescence
View Protocol
ICC
Immunocytochemistry
View Protocol