HSPA5 antibody

Référence FNab10492

Conditionnement : 100ug

Marque : FineTest

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Synonyms:Endoplasmic reticulum chaperone BiP|78 kDa glucose-regulated protein (GRP-78)|Binding-immunoglobulin protein (BiP)|Heat shock protein 70 family protein 5 (HSP70 family protein 5)|Heat shock protein family A member 5|Immunoglobulin heavy chain-binding protein|HSPA5|GRP78 antibody
Catalogue No.:FNab10492Reactivity:Human, Mouse, Rat
Host:MouseTested Application:ELISA, WB, IHC, IF
Clonality:monoclonalIsotype:IgG1
Size
100µg Inquiry
Dispatch Time: About 3 working days
Product Name
HSPA5 antibody
Catalogue No.
FNab10492
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG1
Clone ID
3F8
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
Endoplasmic reticulum chaperone BiP
Alternative Names
Endoplasmic reticulum chaperone BiP|78 kDa glucose-regulated protein (GRP-78)|Binding-immunoglobulin protein (BiP)|Heat shock protein 70 family protein 5 (HSP70 family protein 5)|Heat shock protein family A member 5|Immunoglobulin heavy chain-binding protein|HSPA5|GRP78 antibody
UniProt ID
P11021
Observed MW
70-78 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:2000-1:20000; IHC: 1:50-1:200; IF: 1:50-1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab10492(GRP78/BIP antibody) at dilution of 1:5000
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab10492(GRP78/BIP antibody) at dilution of 1:50
Background
GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER).It is a constitutively expressed resident protein of the ER in all eukaryotic cells. Recently it has been reported that GRP78 is associated with apoptosis or inhibition of cancer cell growth.

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