HSV 2 (strain HG52) Glycoprotein E/gE Protein (His)
Référence TMPY-06900-20ug
Conditionnement : 20ug
Marque : TargetMol
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HSV 2 (strain HG52) Glycoprotein E/gE Protein (His)
Copy Product InfoHerpes simplex virus type 2 (HSV-2) is the predominant cause of genital ulcer disease in human. Glycoprotein E (gE) and glycoprotein I (gI) are expressed as a heterodimer on the surface of Herpes simplex virus (HSV). Glycoprotein E binds Fc domain of immunoglobulin G (IgG) and inhibits activities mediated by the IgG Fc domain, contributing to immune evasion by HSV.
For research use only—not for human use. No sales to individuals. Use as intended only.
User Guide of Recombinant Proteins
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Herpes simplex virus type 2 (HSV-2) is the predominant cause of genital ulcer disease in human. Glycoprotein E (gE) and glycoprotein I (gI) are expressed as a heterodimer on the surface of Herpes simplex virus (HSV). Glycoprotein E binds Fc domain of immunoglobulin G (IgG) and inhibits activities mediated by the IgG Fc domain, contributing to immune evasion by HSV. |
| Species | HSV2 |
| Expression System | Baculovirus Insect Cells |
| Tag | C-His |
| Accession Number | P89475 |
| Construction | A DNA sequence encoding the HSV 2 ((strain HG52) (HSV2)) gE/glycoprotein E (translated amino acids of P89475) (Met1-Arg414) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Ala 21 |
| Protein Purity | ≥ 90 % as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 250 mM Nacl, 10% glycerol, pH 8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Research Background | Herpes simplex virus type 2 (HSV-2) is the predominant cause of genital ulcer disease in human. Glycoprotein E (gE) and glycoprotein I (gI) are expressed as a heterodimer on the surface of Herpes simplex virus (HSV). Glycoprotein E binds Fc domain of immunoglobulin G (IgG) and inhibits activities mediated by the IgG Fc domain, contributing to immune evasion by HSV. |
| Molecular Weight | 44.53 kDa (predicted); 49.31 kDa (reducing conditions) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |