Human Beta-thromboglobulin ELISA Kit
Référence MBS762705-96
Conditionnement : 96-Strip-Wells
Marque : MyBiosource
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Beta-Thromboglobulin (BETA-TG) ELISA Kit for Human
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS762705Background: beta-Thromboglobulin, is a chemokine protein secreted by platelets. It is a type of chemokine ligand 7. Along with platelet factor 4, beta-TG is one of the best-characterized platelet-specific proteins. beta-TG and PF4 are stored in platelet alpha… More details
Product Overview
Online Datasheet in PDFProduct Name
Beta-thromboglobulin (Beta-TG), ELISA Kit
Full Product Name
Human Beta-thromboglobulin ELISA Kit
Product Gene Name
Beta-TG elisa kit
Product Synonym Names
b-TG (b-Thromboglobulin)/Beta-TG
Species Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernatant and other biological samples
Detection Range
0.313-20ng/ml
Sensitivity
0.188ng/ml
Specificity
Specifically recognize Beta-TG, no obvious cross reaction with other analogues
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Inter-assay Precision
Inter-assay Precision: samples with low, medium and high concentration are tested 20 times on three different plates.
Intra-assay Precision
Intra-assay Precision: samples with low, medium and high concentration are tested 20 times on same plate.
Molecular Weight
11,098 Da
OMIM
146930
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Beta-TG elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for Beta-TG purchase
MBS762705 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Beta-thromboglobulin (Beta-TG) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Beta-TG. The ELISA analytical biochemical technique of the MBS762705 kit is based on Beta-TG antibody-Beta-TG antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Beta-TG antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Beta-TG. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Additional Details
NCBI/Uniprot data below describe general gene information for Beta-TG. It may not necessarily be applicable to this product.
NCBI Official Full Name
beta-thromboglobulin-like protein
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 8
NCBI Official Symbol
CXCL8
NCBI Official Synonym Symbols
IL8; NAF; GCP1; LECT; LUCT; NAP1; GCP-1; LYNAP; MDNCF; MONAP; NAP-1
UniProt Protein Name
Interleukin-8
UniProt Synonym Protein Names
C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1
UniProt Gene Name
CXCL8
UniProt Synonym Gene Names
IL8; IL-8; GCP-1; MDNCF; MONAP; NAP-1; LYNAP; NAF
UniProt Entry Name
IL8_HUMAN
NCBI Protein Information
interleukin-8
NCBI Summary for Beta-TG
The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for Beta-TG
IL8: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. Belongs to the intercrine alpha (chemokine CxC) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Cytokine; Motility/polarity/chemotaxis; Secreted
Chromosomal Location of Human Ortholog: 4q13-q21
Cellular Component: extracellular region; extracellular space; intracellular
Molecular Function: chemokine activity; interleukin-8 receptor binding; protein binding
Biological Process: angiogenesis; calcium-mediated signaling; cell cycle arrest; cell motility; cellular protein metabolic process; chemotaxis; embryonic gut development; G-protein coupled receptor protein signaling pathway; immune response; induction of positive chemotaxis; inflammatory response; negative regulation of cell proliferation; negative regulation of G-protein coupled receptor protein signaling pathway; neutrophil activation; neutrophil chemotaxis; positive regulation of angiogenesis; receptor internalization; regulation of cell adhesion; regulation of retroviral genome replication; response to molecule of bacterial origin; signal transduction; unfolded protein response
Show more Protein type: Secreted, signal peptide; Cytokine; Motility/polarity/chemotaxis; Secreted
Chromosomal Location of Human Ortholog: 4q13-q21
Cellular Component: extracellular region; extracellular space; intracellular
Molecular Function: chemokine activity; interleukin-8 receptor binding; protein binding
Biological Process: angiogenesis; calcium-mediated signaling; cell cycle arrest; cell motility; cellular protein metabolic process; chemotaxis; embryonic gut development; G-protein coupled receptor protein signaling pathway; immune response; induction of positive chemotaxis; inflammatory response; negative regulation of cell proliferation; negative regulation of G-protein coupled receptor protein signaling pathway; neutrophil activation; neutrophil chemotaxis; positive regulation of angiogenesis; receptor internalization; regulation of cell adhesion; regulation of retroviral genome replication; response to molecule of bacterial origin; signal transduction; unfolded protein response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with Beta-TG elisa kit
| Reference Product | PubMed Publications |
|---|---|
| CXCR2 elisa kit | >235 publications with Beta-TG and CXCR2 |
| CXCR1 elisa kit | >212 publications with Beta-TG and CXCR1 |
| JUN elisa kit | >169 publications with Beta-TG and JUN |
| CXCL12 elisa kit | >92 publications with Beta-TG and CXCL12 |
| EGFR elisa kit | >22 publications with Beta-TG and EGFR |
| RELA elisa kit | >19 publications with Beta-TG and RELA |
| FOS elisa kit | >8 publications with Beta-TG and FOS |
| DARC elisa kit | >8 publications with Beta-TG and DARC |
| NFKB1 elisa kit | >2 publications with Beta-TG and NFKB1 |
| CEBPB elisa kit | >1 publications with Beta-TG and CEBPB |
Pathways associated with Beta-TG elisa kit
| Products by Pathway | Pathway Diagram |
|---|---|
| AGE-RAGE Signaling Pathway In Diabetic Complications antibodies | AGE-RAGE Signaling Pathway In Diabetic Complications Diagram |
| AGE-RAGE Signaling Pathway In Diabetic Complications antibodies | AGE-RAGE Signaling Pathway In Diabetic Complications Diagram |
| ATF-2 Transcription Factor Network Pathway antibodies | ATF-2 Transcription Factor Network Pathway Diagram |
| ATF4 Activates Genes Pathway antibodies | ATF4 Activates Genes Pathway Diagram |
| Amoebiasis Pathway antibodies | Amoebiasis Pathway Diagram |
| Amoebiasis Pathway antibodies | Amoebiasis Pathway Diagram |
| Bladder Cancer Pathway antibodies | Bladder Cancer Pathway Diagram |
| Bladder Cancer Pathway antibodies | Bladder Cancer Pathway Diagram |
| Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies | Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram |
| Cellular Senescence Pathway antibodies | Cellular Senescence Pathway Diagram |
Diseases associated with Beta-TG elisa kit
| Disease Name | Pubmed Publications |
|---|---|
| Inflammation Antibodies | >732 publications with Beta-TG and Inflammation |
| Necrosis Antibodies | >357 publications with Beta-TG and Necrosis |
| Pulmonary Disease, Chronic Obstructive Antibodies | >97 publications with Beta-TG and Pulmonary Disease, Chronic Obstructive |
| Arthritis, Rheumatoid Antibodies | >60 publications with Beta-TG and Arthritis, Rheumatoid |
| Adenocarcinoma Antibodies | >38 publications with Beta-TG and Adenocarcinoma |
| Breast Neoplasms Antibodies | >28 publications with Beta-TG and Breast Neoplasms |
| Kidney Diseases Antibodies | >22 publications with Beta-TG and Kidney Diseases |
| Pulmonary Fibrosis Antibodies | >19 publications with Beta-TG and Pulmonary Fibrosis |
| Colorectal Neoplasms Antibodies | >18 publications with Beta-TG and Colorectal Neoplasms |
| Fever Antibodies | >16 publications with Beta-TG and Fever |
Organs/Tissues associated with Beta-TG elisa kit
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >843 publications with Beta-TG and Blood |
| Lung Antibodies | >286 publications with Beta-TG and Lung |
| Vascular Antibodies | >224 publications with Beta-TG and Vascular |
| Skin Antibodies | >131 publications with Beta-TG and Skin |
| Bone Antibodies | >77 publications with Beta-TG and Bone |
| Brain Antibodies | >68 publications with Beta-TG and Brain |
| Heart Antibodies | >62 publications with Beta-TG and Heart |
| Muscle Antibodies | >61 publications with Beta-TG and Muscle |
| Intestine Antibodies | >58 publications with Beta-TG and Intestine |
| Bone Marrow Antibodies | >51 publications with Beta-TG and Bone Marrow |
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