Human Catalase, Cat ELISA Kit

Référence MBS703074-96

Conditionnement : 96-Strip-Wells

Marque : MyBiosource

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Téléphone : +1 850 650 7790

Catalase (CAT) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS703074

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CAT has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CAT present is bound by the… More details

Product Overview

Product Name
catalase, ELISA Kit
Full Product Name
Human Catalase, Cat ELISA Kit
Product Gene Name
CAT elisa kit
Product Synonym Names
Human Catalase (CAT) ELISA kit; MGC138422; MGC138424; ; catalase
Species Reactivity
Human
Assay Type
Quantitative Sandwich
Samples
Serum, plasma, tissue homogenates
Detection Range
15.6 pg/ml-1000 pg/ml
Sensitivity
< 3.9 pg/ml
Specificity
This assay has high sensitivity and excellent specificity for detection of human CAT. No significant cross-reactivity or interference between human CAT and analogues was observed.
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
Inter-assay Precision
Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
Molecular Weight
59,756 Da
OMIM
gene 614097
3D Structure
ModBase 3D Structure for P04040
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of CAT elisa kit

Human CAT ELISA Kit – Cat# MBS703074

Other Notes

Small volumes of CAT elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CAT purchase

MBS703074 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the catalase, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CAT. The ELISA analytical biochemical technique of the MBS703074 kit is based on CAT antibody-CAT antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CAT antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CAT. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CAT. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
catalase
NCBI Official Synonym Full Names
catalase
NCBI Official Symbol
CAT
UniProt Protein Name
Catalase
Protein Family
Catalase
UniProt Gene Name
CAT
UniProt Entry Name
CATA_HUMAN
NCBI Protein Information
catalase

NCBI Summary for CAT

This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]
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UniProt Comments for CAT

Function: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.1 PublicationManual assertion based on experiment in:Ref.11

Catalytic activity: 2 H2O2 = O2 + 2 H2O.1 PublicationManual assertion based on experiment in:Ref.11

Cofactor: Heme group.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CAT elisa kit

 Reference Product  PubMed Publications
 SOD1 elisa kit  >178 publications with CAT and SOD1
 SOD2 elisa kit  >140 publications with CAT and SOD2
 GPX1 elisa kit  >128 publications with CAT and GPX1
 SOD3 elisa kit  >26 publications with CAT and SOD3
 GPX4 elisa kit  >23 publications with CAT and GPX4
 XDH elisa kit  >10 publications with CAT and XDH
 FOXO3 elisa kit  >6 publications with CAT and FOXO3
 ALDH2 elisa kit  >5 publications with CAT and ALDH2
 GPX5 elisa kit  >4 publications with CAT and GPX5

Pathways associated with CAT elisa kit

 Products by Pathway  Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 DNA Damage Response (only ATM Dependent) Pathway antibodies  DNA Damage Response (only ATM Dependent) Pathway Diagram
 Detoxification Of Reactive Oxygen Species Pathway antibodies  Detoxification Of Reactive Oxygen Species Pathway Diagram
 Folate Metabolism Pathway antibodies  Folate Metabolism Pathway Diagram
 FoxO Family Signaling Pathway antibodies  FoxO Family Signaling Pathway Diagram
 FoxO Signaling Pathway antibodies  FoxO Signaling Pathway Diagram
 Glyoxylate And Dicarboxylate Metabolism Pathway antibodies  Glyoxylate And Dicarboxylate Metabolism Pathway Diagram

Diseases associated with CAT elisa kit

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1301 publications with CAT and Necrosis
 Asthma Antibodies  >1285 publications with CAT and Asthma
 Diabetes Mellitus Antibodies  >1142 publications with CAT and Diabetes Mellitus
 Hypertension Antibodies  >821 publications with CAT and Hypertension
 Edema Antibodies  >702 publications with CAT and Edema
 Seizures Antibodies  >680 publications with CAT and Seizures
 Disease Progression Antibodies  >561 publications with CAT and Disease Progression
 Brain Ischemia Antibodies  >554 publications with CAT and Brain Ischemia
 Heart Failure Antibodies  >466 publications with CAT and Heart Failure
 Reperfusion Injury Antibodies  >447 publications with CAT and Reperfusion Injury

Organs/Tissues associated with CAT elisa kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >20913 publications with CAT and Brain
 Blood Antibodies  >14650 publications with CAT and Blood
 Nerve Antibodies  >10148 publications with CAT and Nerve
 Muscle Antibodies  >9301 publications with CAT and Muscle
 Eye Antibodies  >5623 publications with CAT and Eye
 Vascular Antibodies  >4628 publications with CAT and Vascular
 Heart Antibodies  >4425 publications with CAT and Heart
 Liver Antibodies  >3999 publications with CAT and Liver
 Skin Antibodies  >3906 publications with CAT and Skin
 Kidney Antibodies  >2810 publications with CAT and Kidney

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