Human CD23 Antibody : FITC
Référence OASB02611
Conditionnement : 25tests
Marque : Aviva Systems Biology
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Human CD23 Antibody : FITC (OASB02611)
| Datasheets/Manuals | Printable datasheet for Human CD23 Antibody : FITC (OASB02611) |
|---|
| Tested Species Reactivity | Human |
|---|---|
| Predicted Species Reactivity | Human |
| Product Format | Liquid. Phosphate buffered saline containing 0.1% sodium azide |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugation | FITC |
| Application | FC, ICC, IHC-F, WB |
| Additional Information | Description: CD23 is a 45 kDa type II integral membrane glycoprotein that is the low affinity receptor for IgE. It also binds to CD21 and the alpha chains of CD11b and CD11c. It is expressed by B cells and monocytes and, weakly, on T cells, follicular dendritic cells, eosinophils, NK cells, Langerhans cells, and platelets. It is upregulated in response to B cell activation, CD40 ligation, or in response to IL-4 or IL-13. CD23 is responsible for regulation of IgE synthesis and may play a role in antigen presentation by B cells and follicular dendritic cells by interacting with CD40. |
| Reconstitution and Storage | Store at 2-8C |
| Immunogen | Purified human tonsil lymphocytes |
| Concentration | Lot specific |
| Specificity | CD23 |
| Gene Symbol | FCER2 |
|---|---|
| Gene Full Name | Fc fragment of IgE receptor II |
| Alias Symbols | CD23, FCE2, CD23A, IGEBF, CLEC4J, BLAST-2 |
| NCBI Gene Id | 2208 |
| Protein Name | low affinity immunoglobulin epsilon Fc receptor |
| Description of Target | The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Uniprot ID | P06734 |
| Protein Accession # | NP_001193948.2 |
| Nucleotide Accession # | NM_001207019.2 |
