Human FcgammaR II/CD32 (Receptor II for the Fc Fragment of IgG) ELISA Kit
Référence MBS2515220-96
Conditionnement : 96Tests
Marque : MyBiosource
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Fcgammar II/CD32 ELISA Kit for Human
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2515220SPECIAL PROMOTIONAL PRICING for a limited time
Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of FcgammaR II/CD32 in human serum, plasma and other biological fluidsPrinciple of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate… More details
Product Overview
Product Name
FcgammaR II/CD32, ELISA Kit
Full Product Name
Human FcgammaR II/CD32 (Receptor II for the Fc Fragment of IgG) ELISA Kit
Product Gene Name
FcgammaR II/CD32 elisa kit
Species Reactivity
Human
Assay Type
Sandwich
Samples
Serum, Plasma, Biological Fluids
Detection Range
46.875-3000pg/mL
Sensitivity
Min: 28.125pg/mL; Max: 3000pg/mL
Specificity
This assay has high sensitivity and excellent specificity for detection of Human FcgammaR II/CD32. No significant cross-reactivity or interference between Human FcgammaR II/CD32 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Human FcgammaR II/CD32 and all the analogues, therefore, cross reaction may still exist.
Preparation and Storage
Store at 4 degree C.
Other Notes
Small volumes of FcgammaR II/CD32 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for FcgammaR II/CD32 purchase
MBS2515220 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the FcgammaR II/CD32, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FcgammaR II/CD32. The ELISA analytical biochemical technique of the MBS2515220 kit is based on FcgammaR II/CD32 antibody-FcgammaR II/CD32 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FcgammaR II/CD32 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FcgammaR II/CD32. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Additional Details
NCBI/Uniprot data below describe general gene information for FcgammaR II/CD32. It may not necessarily be applicable to this product.
NCBI Official Full Name
Fc receptor, IgG, low affinity IIb
NCBI Official Synonym Full Names
Fc receptor, IgG, low affinity IIb
NCBI Official Symbol
Fcgr2b
NCBI Official Synonym Symbols
CD32; Fcgr2; Fcr-2; Fcr-3; Ly-17; LyM-1; Lym-1; fcRII; FcgRII; Fcgr2a; Ly-m20; AI528646; Fc2RII; F630109E10Rik
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor II
UniProt Synonym Protein Names
Fc gamma receptor IIB; Fc-gamma RII; Fc-gamma-RIIB; FcRII; IgG Fc receptor II beta; Lymphocyte antigen 17; Ly-17; CD_antigen: CD32
UniProt Gene Name
Fcgr2
UniProt Synonym Gene Names
Fcgr2b; Ly-17; Fc-gamma RII; Fc-gamma-RIIB; FcRII; Ly-17
UniProt Entry Name
FCGR2_MOUSE
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor II-b; Fc gamma RIIB; Fc-gamma-RII; FcgammaRIIB; fc gamma receptor IIB; fc-gamma RII; fc-gamma-RIIB; igG Fc receptor II beta; lymphocyte antigen 17
UniProt Comments for FcgammaR II/CD32
FCGR2B: a transmembrane receptor for the Fc region of complexed or aggregated immunoglobulin gamma (IgG). Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down modulation of previous state of cell activation triggered via antigen receptors on B cells, T cells or via another Fc receptor. Three splice-variant isoforms have been observed.
Protein type: Oncoprotein; Cell surface; Membrane protein, integral
Cellular Component: recycling endosome; cytoskeleton; cell surface; membrane; integral to plasma membrane; cytoplasm; extracellular region; plasma membrane; integral to membrane; external side of plasma membrane; lipid raft
Molecular Function: protein binding; IgG binding; receptor signaling protein activity; immunoglobulin binding
Biological Process: receptor-mediated endocytosis; negative regulation of phagocytosis; negative regulation of interleukin-10 production; negative regulation of immune response; negative regulation of acute inflammatory response to antigenic stimulus; antigen processing and presentation of exogenous peptide antigen via MHC class II; defense response; negative regulation of B cell proliferation; endocytic recycling; negative regulation of type I hypersensitivity; mast cell activation; negative regulation of neutrophil apoptosis; negative regulation of humoral immune response mediated by circulating immunoglobulin; cell surface receptor linked signal transduction; response to bacterium; positive regulation of phagocytosis; negative regulation of immunoglobulin production; immune complex clearance; immune response; negative regulation of inflammatory response to antigenic stimulus; immunoglobulin mediated immune response; phagocytosis, engulfment
Show more Protein type: Oncoprotein; Cell surface; Membrane protein, integral
Cellular Component: recycling endosome; cytoskeleton; cell surface; membrane; integral to plasma membrane; cytoplasm; extracellular region; plasma membrane; integral to membrane; external side of plasma membrane; lipid raft
Molecular Function: protein binding; IgG binding; receptor signaling protein activity; immunoglobulin binding
Biological Process: receptor-mediated endocytosis; negative regulation of phagocytosis; negative regulation of interleukin-10 production; negative regulation of immune response; negative regulation of acute inflammatory response to antigenic stimulus; antigen processing and presentation of exogenous peptide antigen via MHC class II; defense response; negative regulation of B cell proliferation; endocytic recycling; negative regulation of type I hypersensitivity; mast cell activation; negative regulation of neutrophil apoptosis; negative regulation of humoral immune response mediated by circulating immunoglobulin; cell surface receptor linked signal transduction; response to bacterium; positive regulation of phagocytosis; negative regulation of immunoglobulin production; immune complex clearance; immune response; negative regulation of inflammatory response to antigenic stimulus; immunoglobulin mediated immune response; phagocytosis, engulfment
Research Articles on FcgammaR II/CD32
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with FcgammaR II/CD32 elisa kit
| Reference Product | PubMed Publications |
|---|---|
| Lyn elisa kit | >2 publications with FcgammaR II/CD32 and Lyn |
| Lpl elisa kit | >2 publications with FcgammaR II/CD32 and Lpl |
| Lilrb3 elisa kit | >1 publications with FcgammaR II/CD32 and Lilrb3 |
Pathways associated with FcgammaR II/CD32 elisa kit
| Products by Pathway | Pathway Diagram |
|---|---|
| B Cell Receptor Signaling Pathway antibodies | B Cell Receptor Signaling Pathway Diagram |
| B Cell Receptor Signaling Pathway antibodies | B Cell Receptor Signaling Pathway Diagram |
| B Cell Receptor Signaling Pathway antibodies | B Cell Receptor Signaling Pathway Diagram |
| FCGR Activation Pathway antibodies | FCGR Activation Pathway Diagram |
| Fc Gamma R-mediated Phagocytosis Pathway antibodies | Fc Gamma R-mediated Phagocytosis Pathway Diagram |
| Fc Gamma R-mediated Phagocytosis Pathway antibodies | Fc Gamma R-mediated Phagocytosis Pathway Diagram |
| Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies | Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram |
| Immune System Pathway antibodies | Immune System Pathway Diagram |
| Innate Immune System Pathway antibodies | Innate Immune System Pathway Diagram |
| Measles Pathway antibodies | Measles Pathway Diagram |
Diseases associated with FcgammaR II/CD32 elisa kit
| Disease Name | Pubmed Publications |
|---|---|
| Autoimmune Diseases Antibodies | >129 publications with FcgammaR II/CD32 and Autoimmune Diseases |
| Lupus Erythematosus, Systemic Antibodies | >67 publications with FcgammaR II/CD32 and Lupus Erythematosus, Systemic |
| Inflammation Antibodies | >47 publications with FcgammaR II/CD32 and Inflammation |
| Disease Models, Animal Antibodies | >44 publications with FcgammaR II/CD32 and Disease Models, Animal |
| Kidney Diseases Antibodies | >26 publications with FcgammaR II/CD32 and Kidney Diseases |
| Necrosis Antibodies | >17 publications with FcgammaR II/CD32 and Necrosis |
| Nervous System Diseases Antibodies | >17 publications with FcgammaR II/CD32 and Nervous System Diseases |
| Lung Diseases Antibodies | >14 publications with FcgammaR II/CD32 and Lung Diseases |
| Anemia Antibodies | >5 publications with FcgammaR II/CD32 and Anemia |
| Malaria Antibodies | >4 publications with FcgammaR II/CD32 and Malaria |
Organs/Tissues associated with FcgammaR II/CD32 elisa kit
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >182 publications with FcgammaR II/CD32 and Blood |
| Spleen Antibodies | >28 publications with FcgammaR II/CD32 and Spleen |
| Bone Antibodies | >21 publications with FcgammaR II/CD32 and Bone |
| Bone Marrow Antibodies | >19 publications with FcgammaR II/CD32 and Bone Marrow |
| Lung Antibodies | >8 publications with FcgammaR II/CD32 and Lung |
| Artery Antibodies | >8 publications with FcgammaR II/CD32 and Artery |
| Liver Antibodies | >5 publications with FcgammaR II/CD32 and Liver |
| Thymus Antibodies | >3 publications with FcgammaR II/CD32 and Thymus |
| Skin Antibodies | >3 publications with FcgammaR II/CD32 and Skin |
| Embryonic Tissue Antibodies | >2 publications with FcgammaR II/CD32 and Embryonic Tissue |
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