Human H3-4 Antibody : APC (Phospho-Ser28)
Référence OAAQ00054-10tests
Conditionnement : 10Tests
Marque : Aviva Systems Biology
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Human H3-4 Antibody : APC (Phospho-Ser28)
Human H3-4 Antibody : APC (Phospho-Ser28) (OAAQ00054)
| Datasheets/Manuals | Printable datasheet for OAAQ00054 |
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| Tested Species Reactivity | Human, Mouse |
|---|---|
| Predicted Species Reactivity | Mouse, Rat |
| Product Format | Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA. |
| Clonality | Monoclonal |
| Clone | HisH3S28-D6 |
| Isotype | Rabbit IgG1k |
| Host | Rabbit |
| Conjugation | APC: Allophycocyanin |
| Application | FC |
| Reconstitution and Storage | 2-8C |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser28 of human phospho Histone H3 |
| Purification | Protein A+G |
| Target Post-Translational Modification | Phospho-Ser28 |
| Application Info | For flow cytometric staining, the suggested use of this reagent is 5 uL per million cells or 5 uL per 100 uL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Reference | Hans F and Dimitrov S. (2001) Oncogene. 20: 3021-3027. Cheung P, Tanner KG, Cheung WL, et al. (2000) Molecular Cell. 5: 905-915. |
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| Gene Symbol | H3-4 |
| Gene Full Name | H3.4 histone |
| Alias Symbols | H3t, H3.4, H3/g, H3FT, HIST3H3 |
| NCBI Gene Id | 8290 |
| Protein Name | histone H3.1t |
| Description of Target | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. |
| Uniprot ID | Q16695 |
| Protein Accession # | NP_003484.1 |
| Nucleotide Accession # | NM_003493.2 |
