Human HAT1 activation kit by CRISPRa

Référence GA105636

Conditionnement : 1kit

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Human HAT1 activation kit by CRISPRa

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SKU
GA105636
HAT1 CRISPRa kit - CRISPR gene activation of human histone acetyltransferase 1
 
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HAT1
Locus ID 8520
Components

GA105636G1, HAT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105636G2, HAT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105636G3, HAT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001033085, NM_003642, NR_027862
UniProt ID O14929
Synonyms histone acetyltransferase 1; KAT1
Summary The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. provided by RefSeq, Jun 2009
SKU Description Size
KN409571 HAT1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit

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