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> Human Histone acetyltransferase MYST3 (KAT6A) activation kit by CRISPRa

Human Histone acetyltransferase MYST3 (KAT6A) activation kit by CRISPRa

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Human Histone acetyltransferase MYST3 (KAT6A) activation kit by CRISPRa

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SKU
GA105379
KAT6A CRISPRa kit - CRISPR gene activation of human lysine acetyltransferase 6A
 

Other products for "KAT6A"

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol KAT6A
Locus ID 7994
Components

GA105379G1, Histone acetyltransferase MYST3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105379G2, Histone acetyltransferase MYST3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105379G3, Histone acetyltransferase MYST3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001099412, NM_001099413, NM_006766, NM_001305878
UniProt ID Q92794
Synonyms MOZ; MRD32; MYST3; RUNXBP2; ZC2HC6A; ZNF220
Summary This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with an autosomal dominant form of cognitive disability. Chromosomal translocations of this gene are associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2017
SKU Description Size
KN412980 KAT6A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit

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