Conditionnement : 1kit
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | KLF4 |
| Locus ID | 9314 |
| Components | GA106206G1, KLF4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106206G2, KLF4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106206G3, KLF4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001314052, NM_004235 |
| UniProt ID | O43474 |
| Synonyms | EZF; GKLF |
| Summary | This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Sep 2015 |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN406691 | KLF4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |