Human MAP2K1 Antibody : FITC (Phospho-Ser298)
Référence OAAQ00159-100tests
Conditionnement : 100Tests
Marque : Aviva Systems Biology
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Human MAP2K1 Antibody : FITC (Phospho-Ser298)
Human MAP2K1 Antibody : FITC (Phospho-Ser298) (OAAQ00159)
| Datasheets/Manuals | Printable datasheet for OAAQ00159 |
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| Tested Species Reactivity | Human, Rat |
|---|---|
| Predicted Species Reactivity | Mouse, Rat |
| Product Format | Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA. |
| Clonality | Monoclonal |
| Clone | MEK1S298-H8 |
| Isotype | Rabbit IgG1k |
| Host | Rabbit |
| Conjugation | FITC: Fluorescein Isothiocyanate |
| Application | FC |
| Reconstitution and Storage | 2-8C |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser298 of human phospho MEK1. |
| Purification | Protein A+G |
| Target Post-Translational Modification | Phospho-Ser298 |
| Application Info | For flow cytometric staining, the suggested use of this reagent is 5 uL per million cells or 5 uL per 100 uL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Reference | Raman M. and Cobb MH., (2003) Curr Biol 13:R886-888. Kuida K., and Boucher DM. (2004) J Biochem 135:653-656. Torii S., et al., (2004) J Biochem, 136:557-561. Yoon S. and Seger R., (2006) Growth Factors 24:21-44. Natel A. et al., (1998) J Biol Chem 273:10475-10484. |
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| Gene Symbol | MAP2K1 |
| Gene Full Name | mitogen-activated protein kinase kinase 1 |
| Alias Symbols | MEL, CFC3, MEK1, MKK1, MAPKK1, PRKMK1 |
| NCBI Gene Id | 5604 |
| Protein Name | dual specificity mitogen-activated protein kinase kinase 1 |
| Description of Target | The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. |
| Uniprot ID | Q02750 |
| Protein Accession # | NP_002746.1 |
| Nucleotide Accession # | NM_002755.3 |
