Human Methylmalonyl Coenzyme A mutase (MUT) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MMUT
Locus ID	4594
Kit Components	GA103041G1, Methylmalonyl Coenzyme A mutase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103041G2, Methylmalonyl Coenzyme A mutase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103041G3, Methylmalonyl Coenzyme A mutase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000255
UniProt ID	P22033
Synonyms	MCM
Summary	This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria. [provided by RefSeq, Jul 2008]