IgG4 (FITC)

Référence MBS6249964-5x0,1mL

Conditionnement : 5x0.1mL

Marque : MyBiosource

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IgG4 Secondary Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6249964

MBS6249964 is a secondary antibody targeting IgG4. Also known as IgG4 (FITC). Reactive in Human. Host: Mouse. More details

Product Overview

Online Datasheet in PDF
Product Name
IgG4, Secondary Antibody
Full Product Name
IgG4 (FITC)
Product Gene Name
IgG4 secondary antibody
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3H2426
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Fluorescein isothiocyanate (FITC).
Purity/Purification
Purified
Specificity
Recognizes the heavy chain of human IgG4 at an epitope in the Fc region. Does not crossreact with IgG1, IgG2, IgG3, IgM or IgA. Species Crossreactivity: chimpanzee
Preparation and Storage
Store at -20 degree C.
Molecular Weight
146,000
Chromosome Location
Chromosome: 14; NC_000014.8 (106090813..106092402, complement). Location: 14q32.33
OMIM
147130
3D Structure
ModBase 3D Structure for P01861
Immunogen
Purified human IgG4.
Conjugate
FITC

Product Categories/Family for IgG4 secondary antibody

Antibodies; IgG4
Applications Tested/Suitable for IgG4 secondary antibody
FLISA, Immunohistochemistry (IHC), Western Blot (WB)

Product References and Citations for IgG4 secondary antibody

1. Jefferis, R. et al. (1985). Immunology Letters. 10:223-252. 2. Agaimy, A. et al. (2010) Am J Surg Pathol. 34:271-8. 3. Strehl, J.D. et al. (2011) Numerous IgG4-positive plasma cells are ubiquitous in diverse localised non-specific chronic inflammatory conditions and need to be distinguished from IgG4-related systemic disorders. J Clin Pathol. Jan 12. 4. Black, C.M. et al. (1991) Immunology. 72:94-8. 5. Fernandez-Becerra, C. (2010) Malar J. 9:29. 6. Lee, H.W. et al. (2008) Korean J Parasitol. 46:195-8.

Other Notes

Small volumes of IgG4 secondary antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IgG4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Ig gamma-4 chain C region
NCBI Official Synonym Full Names
immunoglobulin heavy constant gamma 4 (G4m marker)
NCBI Official Symbol
IGHG4
UniProt Protein Name
Ig gamma-4 chain C region
UniProt Gene Name
IGHG4
UniProt Entry Name
IGHG4_HUMAN

UniProt Comments for IgG4

IGHG4:

Chromosomal Location of Human Ortholog: 14q32.33

Cellular Component: extracellular space; extracellular region

Molecular Function: antigen binding

Biological Process: innate immune response; complement activation, classical pathway; complement activation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with IgG4 secondary antibody

 Products by Pathway  Pathway Diagram
 Classical Antibody-mediated Complement Activation Pathway antibodies  Classical Antibody-mediated Complement Activation Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Creation Of C4 And C2 Activators Pathway antibodies  Creation Of C4 And C2 Activators Pathway Diagram
 FCGR Activation Pathway antibodies  FCGR Activation Pathway Diagram
 Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies  Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Initial Triggering Of Complement Pathway antibodies  Initial Triggering Of Complement Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway antibodies  Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway Diagram
 Role Of Phospholipids In Phagocytosis Pathway antibodies  Role Of Phospholipids In Phagocytosis Pathway Diagram

Organs/Tissues associated with IgG4 secondary antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with IgG4 and Blood