Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant

Référence NB-64-55247-20ug

Conditionnement : 20ug

Marque : Neo Biotech

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Product Information

Biological Activity
Measured in antiviral assays using L929 cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is 0.15-0.9 ng/mL.
Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant
Description
Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant is expressed in yeast. The predicted molecular weight is 19.4 kDa and the accession number is B1AYH7.
Species
Mouse
Expression System
P. pastoris (Yeast)
TagTag Free
Accession NumberB1AYH7
Synonyms
interferon, α2,interferon, alpha 2,Interferon α2/IFNA2,Ifa2
Construction
A DNA sequence encoding the mouse Ifna2 (NP_034633.2) (Cys24-Glu190) was expressed. Predicted N terminal: Cys 24
Protein Purity
> 95 % as determined by SDS-PAGE.
Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant
Molecular Weight19.4 kDa (predicted)
EndotoxinPlease contact us for more information.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution
Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a total of 28 different sequence variants have been described. The three principal subtypes of IFNα-2 are designated α-2a, α-2b, and α-2c. IFNα-2b is being the predominant allele while IFNα-2a is less predominant and IFNα-2c only a minor allelic variant.

Dose Conversion

You can also refer to dose conversion for different animals. More