JUN Detection Antibody
Référence OAOA22002
Conditionnement : 50µg
Marque : Aviva Systems Biology
Contactez votre distributeur local :
Téléphone : +1 850 650 7790
JUN Detection Antibody : Biotin (OAOA22002)
| Datasheets/Manuals | Printable datasheet for JUN Detection Antibody : Biotin (OAOA22002) |
|---|
| Predicted Species Reactivity | Human|Mouse|Rat |
|---|---|
| Product Format | Stored in PBS (pH 7.4) with 0.05% sodium azide, 10mg/ml BSA, 50% glycerol |
| Clonality | Monoclonal |
| Clone | OTI2B2 |
| Isotype | IgG1 |
| Host | Mouse |
| Conjugation | Biotin |
| Application | MlpxA |
| Additional Information | Matched ELISA Pair: OAOA21542 |
| Reconstitution and Storage | -20°C |
| Immunogen | Full length human recombinant protein of human JUN (NM_002228) produced in HEK293T cells. |
| Concentration | 0.5 mg/ml |
| Dilution | 1:250 - 1:1000 |
| Description | JUN biotinylated mouse monoclonal detection antibody, validated for Luminex assays |
| Gene Symbol | JUN |
|---|---|
| Gene Full Name | Jun proto-oncogene, AP-1 transcription factor subunit |
| Alias Symbols | activator protein 1, AP-1, AP1, c-Jun, cJUN, enhancer-binding protein AP1, Jun activation domain binding protein, jun oncogene, p39, proto-oncogene c-Jun, proto-oncogene cJun, transcription factor AP-1, v-jun avian sarcoma virus 17 oncogene homolog, v-jun sarcoma virus 17 oncogene homolog. |
| NCBI Gene Id | 3725 |
| Protein Name | Homo sapiens Jun proto-oncogene, AP-1 transcription factor subunit (JUN), mRNA|Transcription factor AP-1 |
| Description of Target | Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306). |
| Uniprot ID | P05412 |
| Protein Accession # | NP_002219 |
| Nucleotide Accession # | https://www.ncbi.nlm.nih.gov/nuccore/NM_002228 |
