KLH Conjugated Thyrotropin Releasing Hormone (TRH)
Référence MBS2097488-0,01mg
Conditionnement : 0.01mg
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TRH Small Molecule – Thyrotropin Releasing Hormone
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2097488SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2097488 is a small molecule targeting TRH. Also known as KLH Conjugated Thyrotropin Releasing Hormone (TRH). Reactive in Mouse. More details
Product Overview
Product Name
Thyrotropin Releasing Hormone (TRH), Small Molecule
Full Product Name
KLH Conjugated Thyrotropin Releasing Hormone (TRH)
Product Gene Name
TRH small molecule
Product Synonym Names
TRF; Thyrotropin-Releasing Factor; Thyroliberin; Protirelin; Pro-tirelin; Prothyroliberin; TSH-releasing factor
Species Reactivity
Mouse
Form/Format
Freeze-dried powder
Purity/Purification
> 95%
Molecular Weight
Predicted Molecular Weight: 380.4Da
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Expression System
Protein conjugation
Tag
N-terminal His Tag
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Product Categories/Family for TRH small molecule
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for TRH small molecule
Immunogen, SDS-PAGE, Western Blot (WB)
Other Notes
Small volumes of TRH small molecule vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for TRH. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
thyrotropin releasing hormone preproprotein
NCBI Official Synonym Full Names
thyrotropin releasing hormone
NCBI Official Symbol
Trh
NCBI Official Synonym Symbols
Trf; Pro-TRH
UniProt Protein Name
Pro-thyrotropin-releasing hormone
UniProt Synonym Protein Names
Prothyroliberin
Protein Family
Pro-thyrotropin-releasing hormone
UniProt Gene Name
Trh
UniProt Synonym Gene Names
Pro-TRH; TRH; TRF
NCBI Protein Information
thyrotropin releasing hormone
NCBI Summary for TRH
This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The mouse proprotein contains five thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Disruption of this gene results in hypothyroidism, elevated thyroid-stimulating hormone levels, and hyperglycemia. [provided by RefSeq, Apr 2013]
Show more UniProt Comments for TRH
TRH: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. May promote hair shaft elongation, prolonge the hair cycle growth phase (anagen) and antagonized its termination by TGFB2. May also increase proliferation and inhibited apoptosis of hair matrix keratinocytes. Belongs to the TRH family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 6 D1|6 41.03 cM
Cellular Component: cytoplasm; extracellular region; nucleus; plasma membrane; secretory granule
Molecular Function: hormone activity; protein binding; thyrotropin-releasing hormone activity
Biological Process: adult walking behavior; eating behavior; histamine metabolic process; hormone-mediated signaling pathway; negative regulation of glutamate secretion; positive regulation of gamma-aminobutyric acid secretion; positive regulation of insulin secretion; signal transduction
Show more Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 6 D1|6 41.03 cM
Cellular Component: cytoplasm; extracellular region; nucleus; plasma membrane; secretory granule
Molecular Function: hormone activity; protein binding; thyrotropin-releasing hormone activity
Biological Process: adult walking behavior; eating behavior; histamine metabolic process; hormone-mediated signaling pathway; negative regulation of glutamate secretion; positive regulation of gamma-aminobutyric acid secretion; positive regulation of insulin secretion; signal transduction
Research Articles on TRH
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with TRH small molecule
| Reference Product | PubMed Publications |
|---|---|
| Cck small molecule | >64 publications with TRH and Cck |
| Trhr small molecule | >56 publications with TRH and Trhr |
| Nts small molecule | >17 publications with TRH and Nts |
| Grp small molecule | >8 publications with TRH and Grp |
| Oxt small molecule | >8 publications with TRH and Oxt |
| Nps small molecule | >3 publications with TRH and Nps |
| Gnrh1 small molecule | >1 publications with TRH and Gnrh1 |
Pathways associated with TRH small molecule
| Products by Pathway | Pathway Diagram |
|---|---|
| Class A/1 (Rhodopsin-like Receptors) Pathway antibodies | Class A/1 (Rhodopsin-like Receptors) Pathway Diagram |
| G Alpha (q) Signalling Events Pathway antibodies | G Alpha (q) Signalling Events Pathway Diagram |
| GPCR Downstream Signaling Pathway antibodies | GPCR Downstream Signaling Pathway Diagram |
| GPCR Ligand Binding Pathway antibodies | GPCR Ligand Binding Pathway Diagram |
| Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies | Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram |
| Peptide Ligand-binding Receptors Pathway antibodies | Peptide Ligand-binding Receptors Pathway Diagram |
| Signal Transduction Pathway antibodies | Signal Transduction Pathway Diagram |
| Signaling By GPCR Pathway antibodies | Signaling By GPCR Pathway Diagram |
Diseases associated with TRH small molecule
| Disease Name | Pubmed Publications |
|---|---|
| Nervous System Diseases Antibodies | >2028 publications with TRH and Nervous System Diseases |
| Brain Diseases Antibodies | >1707 publications with TRH and Brain Diseases |
| Depressive Disorder Antibodies | >340 publications with TRH and Depressive Disorder |
| THYROTROPIN-RELEASING HORMONE DEFICIENCY Antibodies | >298 publications with TRH and THYROTROPIN-RELEASING HORMONE DEFICIENCY |
| Kidney Diseases Antibodies | >162 publications with TRH and Kidney Diseases |
| Disease Models, Animal Antibodies | >139 publications with TRH and Disease Models, Animal |
| Hypertension Antibodies | >131 publications with TRH and Hypertension |
| Weight Loss Antibodies | >94 publications with TRH and Weight Loss |
| Seizures Antibodies | >94 publications with TRH and Seizures |
| Hypothermia Antibodies | >93 publications with TRH and Hypothermia |
Organs/Tissues associated with TRH small molecule
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >4745 publications with TRH and Brain |
| Embryonic Tissue Antibodies | >68 publications with TRH and Embryonic Tissue |
| Uncharacterized Tissue Antibodies | >1 publications with TRH and Uncharacterized Tissue |