KRAS Antibody: PerCP
Référence MBS8001432-0,1mg
Conditionnement : 0.1mg
Marque : MyBiosource
KRAS Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8001432MBS8001432 is an antibody targeting KRAS. Also known as KRAS Antibody: PerCP. Reactive in Rat. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
KRAS, Polyclonal Antibody
Full Product Name
KRAS Antibody: PerCP
Product Gene Name
anti-KRAS antibody
Product Synonym Names
Rabbit Anti-Human KRAS Polyclonal; Transforming protein p21 Antibody; c-Ki-ras Antibody; K RAS4A Antibody; v Ki ras2 Kirsten rat sarcoma viral oncogene homolog Antibody; PR310 cK ras oncogene Antibody; Oncogene KRAS2 Antibody; KRAS Antibody; KRAS1 Antibody; RASK2 Antibody; K RAS2A Antibody; K RAS p21 protein Antibody; GTPase KRas Antibody; c-K-ras Antibody; K-Ras 2 Antibody; KRAS2 Antibody; c Kirsten ras protein Antibody; K RAS2B Antibody; p21ras Antibody; Cellular c Ki ras2 proto oncogene Antibody; Kirsten rat sarcoma 2 viral (v Ki ras2) oncogene homolog Antibody; Ki-Ras Antibody; RASK_HUMAN Antibody; KI RAS Antibody; NS3 Antibody; K RAS4B Antibody; cK Ras Antibody; KIRSTEN MURINE SARCOMA VIRUS 2 Antibody; NS Antibody; N-terminally processed Antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat
Purity/Purification
Peptide Affinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Detects ~29 kDa. Band is higher than the predicted molecular weight due to post translational modifications.
Preparation and Storage
Store at -20 degree C.
Matching Pairs
Unconjugated Antibody: KRAS (MBS8001417)
PerCP Conjugated Antibody: KRAS (MBS8001432)
PerCP Conjugated Antibody: KRAS (MBS8001432)
Matching Pairs
Unconjugated Antibody: N/A (MBS8001432)
PerCP Conjugated Antibody: KRAS (MBS8001432)
PerCP Conjugated Antibody: KRAS (MBS8001432)
Molecular Weight
21,425 Da
OMIM
190070
Target
KRAS
Immunogen
Synthetic peptide from the C-terminal of Human KRAS (aa. 100-189)
Immunogen Species
Human
Cellular Localization
Cell Membrane; Lipid-Anchor; Cytoplasmic Side; Cytoplasm; Cytosol
Conjugate
PerCP
Storage Buffer
PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide
Product Categories/Family for anti-KRAS antibody
Antibodies; Cell Signaling; G Protein Signaling; Small G Proteins; Ras Family; Cell Signaling; Epigenetics and Nuclear Signaling; Transcription; Cancer
Applications Tested/Suitable for anti-KRAS antibody
Western Blot (WB)
Application Notes for anti-KRAS antibody
WB: 1:1000
Western Blot (WB) of anti-KRAS antibody
Western blot analysis of Rat Kidney showing detection of ~21.6 kDa KRAS protein using Rabbit Anti-KRAS Polyclonal Antibody (SPC-777). Lane 1: Molecular Weight Ladder (MW). Lane 2: Rat Kidney. Load: 15 ug. Block: 5% Skim Milk in 1X TBST. Primary Antibody: Rabbit Anti-KRAS Polyclonal Antibody (SPC-777) at 1:1000 for 2 hours at RT. Secondary Antibody: Goat Anti-Rabbit IgG: HRP at 1:5000 for 1 hour at RT. Color Development: ECL solution for 5 min at RT. Predicted/Observed Size: ~21.6 kDa. Other Band(s): ~29 kDa (PTM).
Other Notes
Small volumes of anti-KRAS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for KRAS. It may not necessarily be applicable to this product.
NCBI Official Full Name
GTPase KRas isoform b
NCBI Official Synonym Full Names
KRAS proto-oncogene, GTPase
NCBI Official Symbol
KRAS
NCBI Official Synonym Symbols
NS; NS3; CFC2; RALD; K-Ras; KRAS1; KRAS2; RASK2; KI-RAS; C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; c-Ki-ras2
UniProt Protein Name
GTPase KRas
UniProt Synonym Protein Names
K-Ras 2; Ki-Ras; c-K-ras; c-Ki-ras
Protein Family
GTPase
UniProt Gene Name
KRAS
UniProt Synonym Gene Names
KRAS2; RASK2
NCBI Protein Information
GTPase KRas
NCBI Summary for KRAS
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for KRAS
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306).
Show more Research Articles on KRAS
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-KRAS antibody
| Reference Product | PubMed Publications |
|---|---|
| EGFR antibody | >3125 publications with KRAS and EGFR |
| BRAF antibody | >2875 publications with KRAS and BRAF |
| PIK3CA antibody | >1232 publications with KRAS and PIK3CA |
| ERBB2 antibody | >415 publications with KRAS and ERBB2 |
| MAP2K1 antibody | >118 publications with KRAS and MAP2K1 |
| RAF1 antibody | >89 publications with KRAS and RAF1 |
| SOS1 antibody | >83 publications with KRAS and SOS1 |
| MAPK1 antibody | >40 publications with KRAS and MAPK1 |
| ARAF antibody | >14 publications with KRAS and ARAF |
| MAPK3 antibody | >8 publications with KRAS and MAPK3 |
Pathways associated with anti-KRAS antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| AGE-RAGE Signaling Pathway In Diabetic Complications antibodies | AGE-RAGE Signaling Pathway In Diabetic Complications Diagram |
| AGE-RAGE Signaling Pathway In Diabetic Complications antibodies | AGE-RAGE Signaling Pathway In Diabetic Complications Diagram |
| ARMS-mediated Activation Pathway antibodies | ARMS-mediated Activation Pathway Diagram |
| Activation Of RAS In B Cells Pathway antibodies | Activation Of RAS In B Cells Pathway Diagram |
| Acute Myeloid Leukemia Pathway antibodies | Acute Myeloid Leukemia Pathway Diagram |
| Acute Myeloid Leukemia Pathway antibodies | Acute Myeloid Leukemia Pathway Diagram |
| Adaptive Immune System Pathway antibodies | Adaptive Immune System Pathway Diagram |
| Alcoholism Pathway antibodies | Alcoholism Pathway Diagram |
| Alcoholism Pathway antibodies | Alcoholism Pathway Diagram |
| Aldosterone-regulated Sodium Reabsorption Pathway antibodies | Aldosterone-regulated Sodium Reabsorption Pathway Diagram |
Diseases associated with anti-KRAS antibody
| Disease Name | Pubmed Publications |
|---|---|
| Carcinoma Antibodies | >4128 publications with KRAS and Carcinoma |
| Colorectal Neoplasms Antibodies | >3249 publications with KRAS and Colorectal Neoplasms |
| Adenocarcinoma Antibodies | >2999 publications with KRAS and Adenocarcinoma |
| Lung Neoplasms Antibodies | >2214 publications with KRAS and Lung Neoplasms |
| Carcinogenesis Antibodies | >1225 publications with KRAS and Carcinogenesis |
| Pancreatic Neoplasms Antibodies | >1147 publications with KRAS and Pancreatic Neoplasms |
| Carcinoma, Non-Small-Cell Lung Antibodies | >1140 publications with KRAS and Carcinoma, Non-Small-Cell Lung |
| Neoplasm Metastasis Antibodies | >1034 publications with KRAS and Neoplasm Metastasis |
| Neoplasms, Experimental Antibodies | >603 publications with KRAS and Neoplasms, Experimental |
| Carcinoma, Pancreatic Ductal Antibodies | >555 publications with KRAS and Carcinoma, Pancreatic Ductal |
Organs/Tissues associated with anti-KRAS antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Lung Antibodies | >2803 publications with KRAS and Lung |
| Blood Antibodies | >851 publications with KRAS and Blood |
| Liver Antibodies | >673 publications with KRAS and Liver |
| Pancreas Antibodies | >543 publications with KRAS and Pancreas |
| Vascular Antibodies | >353 publications with KRAS and Vascular |
| Skin Antibodies | >325 publications with KRAS and Skin |
| Lymph Antibodies | >324 publications with KRAS and Lymph |
| Lymph Node Antibodies | >318 publications with KRAS and Lymph Node |
| Bone Antibodies | >233 publications with KRAS and Bone |
| Intestine Antibodies | >226 publications with KRAS and Intestine |

