L-Lactic acid [79-33-4]
Référence T4845-500mg
Conditionnement : 500mg
Marque : TargetMol
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L-Lactic acid
(Synonyms: L-(+)-Lactic acid, 2-HYDROXYPROPIONIC ACID, (S)-2-Hydroxypropanoic acid) Copy Product Info
L-Lactic acid ((S)-2-Hydroxypropanoic acid) is a natural product produced by the anaerobic glycolysis of pyruvic acid. L-Lactic acid is a sensitive indicator of tissue hypoxia and can be used as a hemodynamic indicator in critically ill patients.
Cas No. 79-33-4
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.85%
Color:White
COA HNMR HPLC
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | L-Lactic acid ((S)-2-Hydroxypropanoic acid) is a natural product produced by the anaerobic glycolysis of pyruvic acid. L-Lactic acid is a sensitive indicator of tissue hypoxia and can be used as a hemodynamic indicator in critically ill patients. |
| Targets & IC50 | LDHA:3 nM |
| In vitro | METHODS: Mouse CD4+CD25-T cells were treated with low-glucose medium containing L-Lactic acid (5-20 mM), and Teff proliferation was detected by Flow cytometry. RESULTS: L-Lactic acid had a sustained inhibitory effect on T cell proliferation, and apoptosis-independent effect. [1] METHODS: T cells were cultured in medium containing L-Lactic acid (20 mM), and ROS levels were measured using ROS and superoxide detection assay kits. RESULTS: A significant reduction in ROS and O2- production was observed in L-Lactic acid-treated T cells. [2] |
| In vivo | METHODS: To study its effect on swimming endurance, L-Lactic acid (25-50 mg/kg in 0.9% NaCl) was administered intraperitoneally to ICR mice. RESULTS: L-Lactic acid enhanced the swimming endurance of mice, and the effect was dose-dependent. [3] METHODS: To investigate the effect on endotoxemia, L-Lactic acid (80 mg/kg) was intraperitoneally injected into mice, and 20 h later, a lethal dose of LPS (25 mg/kg) was intraperitoneally injected into mice to induce infectious shock. RESULTS: L-Lactic acid significantly inhibited LPS-induced cytokine induction in mice following endotoxemia.L-Lactic acid treatment decreased glucose uptake and lactate output during LPS stimulation. [4] |
| Synonyms | L-(+)-Lactic acid, 2-HYDROXYPROPIONIC ACID, (S)-2-Hydroxypropanoic acid |
| Molecular Weight | 90.08 |
| Formula | C3H6O3 |
| Cas No. | 79-33-4 |
| Smiles | [C@@H](C(O)=O)(C)O |
| Relative Density. | 1.19 g/cm3. Temperature:25 °C.;1.2 g/cm3. Temperature:25 °C. |
| Storage | Store at low temperature,Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 262 mg/mL (2908.53 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 5% DMSO+95% Saline: 2.63 mg/mL (29.2 mM), Solution. Saline: 50 mg/mL (555.06 mM), Solution. 10% DMSO+90% Saline: 5 mg/mL (55.51 mM), Solution. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||