L-SelenoMethionine [3211-76-5]

Commande minimum 2

Référence T5372-50mg

Conditionnement : 50mg

Marque : TargetMol

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L-SelenoMethionine

(Synonyms: L-(+)-Selenomethionine) Copy Product Info
L-SelenoMethionine (L-(+)-Selenomethionine) is a naturally occurring amino acid. It promotes cell cycle progression and elevates the expression of the antioxidant enzymes thioredoxin reductase, glutathione reductase.
L-SelenoMethionine
Cas No. 3211-76-5
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.67%
Color:White
COA LCMS HNMR

Product Introduction

Bioactivity
Description
L-SelenoMethionine (L-(+)-Selenomethionine) is a naturally occurring amino acid. It promotes cell cycle progression and elevates the expression of the antioxidant enzymes thioredoxin reductase, glutathione reductase.
In vitro
At 5 μM, L-selenomethionine selectively induces apoptosis in LNCaP prostate cancer cells without affecting non-cancerous cells [1]. c-Myc, cyclin C, proliferating cell nuclear antigen, cyclin-dependent kinase (cdk)1, cdk2, cdk4, cyclin B and cyclin D2 mRNA levels were lower in selenium-deficient cells than in the cells supplemented with 0.25 micromol/L selenomethionine. The phosphorylation state of total cellular protein was higher (57%) in selenium-supplemented cells than in selenium-deficient cells [2].
SynonymsL-(+)-Selenomethionine
Chemical Properties
Molecular Weight196.11
FormulaC5H11NO2Se
Cas No.3211-76-5
Smiles[C@@H](C(O)=O)(CC[Se]C)N
Relative Density.no data available
Storage & Solubility Information
StorageStore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: < 1 mg/mL (insoluble or slightly soluble), Sonication is recommended.
H2O: 27.5 mg/mL (140.23 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM5.0992 mL25.4959 mL50.9918 mL254.9590 mL
5 mM1.0198 mL5.0992 mL10.1984 mL50.9918 mL
10 mM0.5099 mL2.5496 mL5.0992 mL25.4959 mL
20 mM0.2550 mL1.2748 mL2.5496 mL12.7479 mL
50 mM0.1020 mL0.5099 mL1.0198 mL5.0992 mL
100 mM0.0510 mL0.2550 mL0.5099 mL2.5496 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.