Lipid A (Alcaligenes faecalis)

Référence 24018-s

Conditionnement : 0.1mg

Marque : Peptide Institute

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Lipid A (Alcaligenes faecalis)

Code:
24018-s
Name:
Lipid A (Alcaligenes faecalis)
2-[(R)-3-(Decanoyloxy)tetradecanoylamino]-2-deoxy-6-O-(2-deoxy-2-{(R)-3-[(R)-3-hydroxydodecanoyloxy]tetradecanoylamino}-3-O-[(R)-3-hydroxytetradecanoyl]-β-D-glucopyranosyl)-3-O-[(R)-3-hydroxytetradecanoyl]-α-D-glucopyranose 1,4′-bisphosphate
(Triethylammonium Form)
(M.W. 1758.3) C90H170N2O26P2
Vaccine Adjuvant Candidate / Active Principle of Low-Toxic Endotoxin
Storage:
-20 ℃
Source:
Alcaligenes faecalis

Solubility: DMSO (0.1 mM)

Structure:
structure of Lipid A (Alcaligenes faecalis)
Category:
Carbohydrates and Conjugates

This compound is distributed under the license of National Institutes of Biomedical Innovation, Health and Nutrition and The Research Foundation for Microbial Diseases of Osaka University.

reference

  1. Y. Wang, K. Hosomi, A. Shimoyama, K. Yoshii, H. Yamaura, T. Nagatake, T. Nishino, H. Kiyono, K. Fukase, and J. Kunisawa, Vaccines, 8, 395 (2020). (Adjuvant Activity)
  2. K. Yoshii, K. Hosomi, A. Shimoyama, Y. Wang, H. Yamaura, T. Nagatake, H. Suzuki, H. Lan, H. Kiyono, K. Fukase, and J. Kunisawa, Microorganisms, 8, 1102 (2020). (Adjuvant Activity)
  3. A. Shimoyama, F. Di Lorenzo, H. Yamaura, K. Mizote, A. Palmigiano, M.D. Pither, I. Speciale, T. Uto, S. Masui, L. Sturiale, D. Garozzo, K. Hosomi, N. Shibata, K. Kabayama, Y. Fujimoto, A. Silipo, J. Kunisawa, H. Kiyono, A. Molinaro, and K. Fukase, Angew. Chem. Int. Ed., 60, 10023 (2021). (Chem. Synthesis)