M CSF Protein
Référence OPPA00573
Conditionnement : 2µg
Marque : Aviva Systems Biology
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| Datasheets/Manuals | Printable datasheet for OPPA00573 |
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| Predicted Species Reactivity | Human |
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| Product Format | Lyophilized10mM Sodium Phosphate (pH 8.0) & 50mM NaCl |
| Host | E. Coli |
| Reconstitution and Storage | It is recommended to reconstitute the lyophilized M-CSF in sterile 18M Omega-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Lyophilized Macrophage Colony Stimulating Factor although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution MCSF should be stored at 4C between 2-7 days and for future use below -18C. Please prevent freeze-thaw cycles. |
| Purification | MCSF is purified by proprietary chromatographic techniques. |
| Concentration | 1 mg/ml (prior to lyophilization) |
| Purity | Greater than 97.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
| Biological Activity | The ED50, calculated by the dose-dependent stimulation of the proliferation of murine M-NFS-60 indicator cells was found to be < 1.4 - 2.1 ng/mL. |
| Protein Sequence | MEEVSEYCSH MIGSGHLQSL QRLIDSQMET SCQITFEFVD QEQLKDPVCY LKKAFLLVQD IMEDTMRFRD NTPNAIAIVQ LQELSLRLKS CFTKDYEEHD KACVRTFYET PLQLLEKVKN VFNETKNLLD KDWNIFSKNC NNSFAECSSQ GHERQSEGS |
| Gene Symbol | M CSF |
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| Alias Symbols | MCSF, CSF-1 |
| NCBI Gene Id | 1435 |
| Protein Name | Macrophage colony-stimulating factor 1 |
| Description of Target | Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. MCSF induces cells of the monocyte/macrophage lineage. MCSF plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Macrophage Colony Stimulating Factor Human Recombinant produced in E.coli is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing 2 x 159 amino acids. |
| Uniprot ID | P09603 |
| Protein Accession # | NP_000748.3 |
| Protein Size (# AA) | Recombinant |
| Molecular Weight | 37 kDa |