Malachite green [569-64-2]
Référence T20019-50mg
Conditionnement : 50mg
Marque : TargetMol
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Malachite green [569-64-2]
Malachite green
(Synonyms: Solid Green O, Solid Green Crystals O) Copy Product InfoMalachite green (Solid Green Crystals O) is an N-methylated diaminotriphenylmethane dye used for coloring.
Cas No. 569-64-2
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.99%
Appearance:Solid
Color:Green
COA HNMR LCMS
Product Introduction
Malachite green AI Summary
Malachite green has a bioactivity related to the dissociation constant, with a measured value of Kd = 40.0 nM. It also exhibits cytotoxicity activity against human HepG2 cells, as indicated by its IC50 value of 300.0 nM, suggesting its potency in inhibiting the viability of these cells..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Malachite green (Solid Green Crystals O) is an N-methylated diaminotriphenylmethane dye used for coloring. |
| Synonyms | Solid Green O, Solid Green Crystals O |
| Cell Research | Instructions I. Solution preparation: 1. Preparation of storage solution: Dissolve Safranin O in deionized water to prepare a 0.1%-1% (w/v) stock solution. If a higher solubility is required, a small amount of ethanol can be added to help dissolve. Note: The stock solution should be stored in a dark place and refrigerated to avoid dye degradation. 2. Preparation of working solution: Dilute the storage solution to the required working solution according to experimental requirements. II. Biological tissue staining 1. Sample fixation: Fix the tissue sample in formalin solution, dehydrate and embed. After slicing, prepare the tissue slices for staining. 2. Staining steps: 1) Place the tissue slices in Safranin O staining solution. The staining time is adjusted according to the sample type, generally 2-5 minutes. 2) If contrast staining is required, Fast Green or other suitable dyes can be used. 3) Use 70%-95% ethanol for graded decolorization until the dye in non-target areas is removed. 4) Sealing: Seal the slide with neutral gum or other suitable sealing agent to prevent the sample from drying or dye loss. 5) Microscopic observation: Use an optical microscope to observe the staining results: Cell nuclei and cartilage matrix will appear red. Collagen fibers, extracellular matrix, etc. will appear green (if Fast Green is used as a contrast dye). Precautions: 1) Operation safety: Wear gloves and goggles when using to avoid contact of dye with skin or eyes. 2) Dye storage: Safranin O is light-sensitive and should be stored in a dark place and refrigerated. Ensure that there is no precipitation in the dye before use. 3) Contrast staining: Select a suitable contrast stain (such as Fast Green) according to the purpose of the experiment. The above information is based on published literature. Experimental procedures should be appropriately modified to meet specific research demands. |
| Molecular Weight | 364.91 |
| Formula | C23H25ClN2 |
| Cas No. | 569-64-2 |
| Smiles | [Cl-].CN(C)c1ccc(cc1)C(=C1C=CC(C=C1)=[N+](C)C)c1ccccc1 |
| Relative Density. | 1.0448 g/cm3 (Estimated) |
| Storage | Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 125 mg/mL (342.55 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+90% Saline: 10 mg/mL (27.4 mM), Solution. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||