Mouse Viperin ELISA Kit
Référence MBS456929-48
Conditionnement : 48Tests
Marque : MyBiosource
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Viperin (RSAD2) ELISA Kit for Mouse
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS456929Intended Uses: The kit is a sandwich enzyme immunoassay for the in vitro quantitative measurement of Viperin in mouse serum, plasma, tissue homogenates or other biological fluids.Principle of the Assay: The microtiter plate provided in this kit has been… More details
Product Overview
Online Datasheet in PDFProduct Name
Viperin (Rsad2), ELISA Kit
Full Product Name
Mouse Viperin ELISA Kit
Product Gene Name
Rsad2 elisa kit
Product Synonym Names
Cig5; RSAD2; vig1; Radical S-Adenosyl Methionine Domain Containing 2; Viperin,Endoplasmic Reticulum-Associated,Interferon-Inducible; Cytomegalovirus-induced gene 5
Species Reactivity
Mouse
Assay Type
Quantitative Sandwich
Samples
Serum, plasma, tissue homogenates or other biological fluids
Detection Range
0.156-10ng/mL
Sensitivity
<0.072ng/mL.
Specificity
This assay has high sensitivity and excellent specificity for detection of Viperin. No significant cross-reactivity or interference between Viperin and analogues was observed.
Inter-assay Precision
Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Viperin were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Inter-Assay: CV<12%
Intra-assay Precision
Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Viperin were tested 20 times on one plate, respectively. Intra-Assay: CV<10%
Molecular Weight
41,524 Da
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Rsad2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for Rsad2 purchase
MBS456929 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Viperin (Rsad2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Rsad2. The ELISA analytical biochemical technique of the MBS456929 kit is based on Rsad2 antibody-Rsad2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Rsad2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Rsad2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Additional Details
NCBI/Uniprot data below describe general gene information for Rsad2. It may not necessarily be applicable to this product.
NCBI Official Full Name
radical S-adenosyl methionine domain-containing protein 2
NCBI Official Synonym Full Names
radical S-adenosyl methionine domain containing 2
NCBI Official Symbol
Rsad2
NCBI Official Synonym Symbols
Vig1; cig5; 2510004L01Rik
UniProt Protein Name
Radical S-adenosyl methionine domain-containing protein 2
UniProt Synonym Protein Names
Viperin; Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible
Protein Family
Radical S-adenosyl methionine domain-containing protein
UniProt Gene Name
Rsad2
NCBI Protein Information
radical S-adenosyl methionine domain-containing protein 2
UniProt Comments for Rsad2
RSAD2: Interferon-inducible iron-sulfur (4FE-4S) cluster- binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV), hepatitis C virus (HCV), west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV), and human immunodeficiency virus (HIV-1). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphospate synthase (FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63'-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins. Belongs to the radical SAM superfamily. RSAD2 family.
Chromosomal Location of Human Ortholog: 12|12 A2
Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; fibrillar center; lipid droplet; membrane; mitochondrial inner membrane; mitochondrial outer membrane; mitochondrion
Molecular Function: 4 iron, 4 sulfur cluster binding; catalytic activity; iron-sulfur cluster binding; metal ion binding; protein binding; protein self-association
Biological Process: CD4-positive, alpha beta T cell differentiation; defense response to virus; immune system process; innate immune response; negative regulation of protein secretion; negative regulation of viral genome replication; ossification; positive regulation of toll-like receptor 7 signaling pathway; positive regulation of toll-like receptor 9 signaling pathway; regulation of ossification; response to virus
Show more Chromosomal Location of Human Ortholog: 12|12 A2
Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; fibrillar center; lipid droplet; membrane; mitochondrial inner membrane; mitochondrial outer membrane; mitochondrion
Molecular Function: 4 iron, 4 sulfur cluster binding; catalytic activity; iron-sulfur cluster binding; metal ion binding; protein binding; protein self-association
Biological Process: CD4-positive, alpha beta T cell differentiation; defense response to virus; immune system process; innate immune response; negative regulation of protein secretion; negative regulation of viral genome replication; ossification; positive regulation of toll-like receptor 7 signaling pathway; positive regulation of toll-like receptor 9 signaling pathway; regulation of ossification; response to virus
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with Rsad2 elisa kit
| Reference Product | PubMed Publications |
|---|---|
| Ifit1 elisa kit | >18 publications with Rsad2 and Ifit1 |
| Mx2 elisa kit | >11 publications with Rsad2 and Mx2 |
| Usp18 elisa kit | >10 publications with Rsad2 and Usp18 |
| Ifit3 elisa kit | >9 publications with Rsad2 and Ifit3 |
| Irf7 elisa kit | >9 publications with Rsad2 and Irf7 |
| Ifit2 elisa kit | >8 publications with Rsad2 and Ifit2 |
| Ifih1 elisa kit | >6 publications with Rsad2 and Ifih1 |
| Dhx58 elisa kit | >3 publications with Rsad2 and Dhx58 |
| Cmpk2 elisa kit | >2 publications with Rsad2 and Cmpk2 |
| Oasl1 elisa kit | >1 publications with Rsad2 and Oasl1 |
Pathways associated with Rsad2 elisa kit
| Products by Pathway | Pathway Diagram |
|---|---|
| Influenza A Pathway antibodies | Influenza A Pathway Diagram |
| Influenza A Pathway antibodies | Influenza A Pathway Diagram |
Diseases associated with Rsad2 elisa kit
| Disease Name | Pubmed Publications |
|---|---|
| Liver Diseases Antibodies | >16 publications with Rsad2 and Liver Diseases |
| Inflammation Antibodies | >15 publications with Rsad2 and Inflammation |
| Nervous System Diseases Antibodies | >13 publications with Rsad2 and Nervous System Diseases |
| Influenza, Human Antibodies | >7 publications with Rsad2 and Influenza, Human |
| Cardiovascular Diseases Antibodies | >5 publications with Rsad2 and Cardiovascular Diseases |
| Necrosis Antibodies | >4 publications with Rsad2 and Necrosis |
| Disease Models, Animal Antibodies | >4 publications with Rsad2 and Disease Models, Animal |
| Carcinoma, Hepatocellular Antibodies | >3 publications with Rsad2 and Carcinoma, Hepatocellular |
| Kidney Diseases Antibodies | >3 publications with Rsad2 and Kidney Diseases |
| Lung Diseases Antibodies | >3 publications with Rsad2 and Lung Diseases |
Organs/Tissues associated with Rsad2 elisa kit
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >31 publications with Rsad2 and Blood |
| Liver Antibodies | >14 publications with Rsad2 and Liver |
| Joint Antibodies | >6 publications with Rsad2 and Joint |
| Kidney Antibodies | >6 publications with Rsad2 and Kidney |
| Bone Antibodies | >5 publications with Rsad2 and Bone |
| Embryonic Tissue Antibodies | >3 publications with Rsad2 and Embryonic Tissue |
| Spleen Antibodies | >3 publications with Rsad2 and Spleen |
| Bone Marrow Antibodies | >3 publications with Rsad2 and Bone Marrow |
| Eye Antibodies | >2 publications with Rsad2 and Eye |
| Thymus Antibodies | >1 publications with Rsad2 and Thymus |