MST3 Antibody

Référence MBS8582407-0,1mL-HRP

Conditionnement : 0.1mL(HRP)

Marque : MyBiosource

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MST3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8582407

MBS8582407 is an antibody targeting MST3. Also known as MST3 Antibody. Reactive in Human, Mouse, Rat, Monkey. Host: Rabbit. Rabbit polyclonal antibody to MST3 More details

Product Overview

Online Datasheet in PDF
Product Name
MST3, Polyclonal Antibody
Full Product Name
MST3 Antibody
Product Gene Name
anti-MST3 antibody
Product Synonym Gene Name
STK24
Product Synonym Names
MST3; STK3; Serine/threonine-protein kinase 24; Mammalian STE20-like protein kinase 3; MST-3; STE20-like kinase MST3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Monkey
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of MST3 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
49,308 Da
Chromosome Location
Chromosome: 13; NC_000013.10 (99102455..99229396, complement). Location: 13q31.2-q32.3
OMIM
604984
3D Structure
ModBase 3D Structure for Q9Y6E0
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human MST3. The exact sequence is proprietary.

Product Categories/Family for anti-MST3 antibody

Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MST3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-MST3 antibody
WB: 1:500-1:1000
IHC: 1:50-1:200

Other Notes

Small volumes of anti-MST3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MST3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
serine/threonine-protein kinase 24 isoform b
NCBI Official Synonym Full Names
serine/threonine kinase 24
NCBI Official Symbol
STK24
NCBI Official Synonym Symbols
MST3; STK3; MST3B; STE20
UniProt Protein Name
Serine/threonine-protein kinase 24
UniProt Synonym Protein Names
Mammalian STE20-like protein kinase 3; MST-3; STE20-like kinase MST3Cleaved into the following 2 chains:Serine/threonine-protein kinase 24 36 kDa subunit; Alternative name(s):; Mammalian STE20-like protein kinase 3 N-terminal; MST3/NSerine/threonine-protein kinase 24 12 kDa subunit; Alternative name(s):; Mammalian STE20-like protein kinase 3 C-terminal
Protein Family
Serine/threonine-protein kinase
UniProt Gene Name
STK24
UniProt Synonym Gene Names
MST3; STK3; MST-3; MST3/N; MST3/C
UniProt Entry Name
STK24_HUMAN
NCBI Protein Information
serine/threonine-protein kinase 24; STE20-like kinase 3; STE20-like kinase MST3; sterile 20-like kinase 3; mammalian STE20-like protein kinase 3; serine/threonine kinase 24 (STE20 homolog, yeast)

NCBI Summary for MST3

The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000 [PubMed 10644707]).[supplied by OMIM, Mar 2008]
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UniProt Comments for MST3

MST3: a protein kinase of the STE20 family. Activated by caspase-mediated cleavage

Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.1; Protein kinase, STE; STE group; STE20 family; YSK subfamily

Chromosomal Location of Human Ortholog: 13q31.2-q32.3

Cellular Component: nucleoplasm; membrane; cytoplasm; nucleolus; nucleus; cytosol

Molecular Function: protein serine/threonine kinase activity; protein binding; metal ion binding; ATP binding; receptor signaling protein serine/threonine kinase activity; protein kinase activity

Biological Process: regulation of axon regeneration; response to hydrogen peroxide; apoptosis; protein amino acid autophosphorylation; signal transduction; negative regulation of cell migration; protein amino acid phosphorylation; induction of apoptosis by oxidative stress; cell structure disassembly during apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MST3 antibody

 Reference Product  PubMed Publications
 PDCD10 antibody  >4 publications with MST3 and PDCD10
 CASP3 antibody  >2 publications with MST3 and CASP3
 STK38L antibody  >1 publications with MST3 and STK38L

Pathways associated with anti-MST3 antibody

 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptotic Cleavage Of Cellular Proteins Pathway antibodies  Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram

Diseases associated with anti-MST3 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5 publications with MST3 and Neoplasms
 Nervous System Diseases Antibodies  >4 publications with MST3 and Nervous System Diseases
 Congenital Abnormalities Antibodies  >2 publications with MST3 and Congenital Abnormalities
 Cardiovascular Diseases Antibodies  >2 publications with MST3 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >1 publications with MST3 and Disease Models, Animal
 Brain Diseases Antibodies  >1 publications with MST3 and Brain Diseases
 Inflammation Antibodies  >1 publications with MST3 and Inflammation

Organs/Tissues associated with anti-MST3 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >4 publications with MST3 and Nerve
 Vascular Antibodies  >2 publications with MST3 and Vascular
 Eye Antibodies  >2 publications with MST3 and Eye
 Placenta Antibodies  >2 publications with MST3 and Placenta
 Ganglia Antibodies  >1 publications with MST3 and Ganglia
 Brain Antibodies  >1 publications with MST3 and Brain