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> Nanog (Early Embryo Specific Expression NK Family Gene, Embryonic Stem Cell Specific Homeobox Protein, ENK, Homeobox Transcription Factor Nanog, Nanog Homeobox)

Nanog (Early Embryo Specific Expression NK Family Gene, Embryonic Stem Cell Specific Homeobox Protein, ENK, Homeobox Transcription Factor Nanog, Nanog Homeobox)

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Référence N0019-01B-100ug

Conditionnement : 100ug

Marque : US Biological

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N0019-01B Nanog (Early Embryo Specific Expression NK Family Gene, Embryonic Stem Cell Specific Homeobox Protein, ENK, Homeobox Transcription Factor Nanog, Nanog Homeobox)

Clone Type
Polyclonal
Host
rabbit
Source
human
Swiss Prot
Q9H9S0
Isotype
IgG
Grade
Affinity Purified
Applications
WB
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
-20°C

The transcriptional factor Nanog functions in maintaining pluripotency in cooperation with other key genes such as Oct4. Oct4 and Sox2 bind to the Nanog promoter in mouse and human embryonic stem cell. Nanog levels allow stem cells to balance the creation of lineage-committed and undifferentiated cells.

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 1:500-1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Source: human|Concentration: ~1mg/ml |Form: Supplied as a liquid in PBS, 0.02% sodium azide.|Purity: Purified by immunoaffinity chromatography.|Immunogen: Synthetic peptide corresponding to an internal sequence of the human Nanog protein.|Specificity: Recognizes human Nanog.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Synthetic peptide corresponding to an internal sequence of the human Nanog protein.
Form
Supplied as a liquid in PBS, 0.02% sodium azide.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human Nanog.
References
Clark, A.T., Rodriguez, R.T., Bodnar, M.S., Abeyta, M.J., Cedars, M.I., Turek, P.J.,|Firpo, M.T. and Reijo Pera, R.A. Human STELLAR, NANOG, and GDF3 genes are|expressed in pluripotent cells and map to chromosome 12p13, a hotspot for|teratocarcinoma. (2004) Stem Cells 22:169-179|Mitsui, K., Tokuzawa,Y., Itoh, H., Segawa, K., Murakami, M., Takahashi, K.,|Maruyama, M., Maeda, M. and Yamanaka, S. The homeoprotein Nanog is required|for maintenance of plurioteincy in mouse epiblast and ES cells. (2003) Cell|113:631-642