NEK1 Antibody
Référence OAGA07836
Conditionnement : 100ul
Marque : Aviva Systems Biology
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| Datasheets/Manuals | Printable datasheet for NEK1 Antibody (OAGA07836) |
|---|
| Predicted Species Reactivity | Human|Mouse |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | ICC|IF|IP|WB |
| Reconstitution and Storage | -20°C or -80°C|2°C to 8°C |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Nek1. The exact sequence is proprietary. |
| Purification | Affinity Purified |
| Concentration | 0.33 mg/ml |
| Preservative | 0.025% ProClin 300 |
| Application Info | Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
| Gene Symbol | NEK1 |
|---|---|
| Gene Full Name | NIMA related kinase 1 |
| Alias Symbols | ALS24, never in mitosis A-related kinase 1, NIMA (never in mitosis gene a)-related kinase 1, nimA-related protein kinase 1, NY-REN-55, protein-serine/threonine kinase, renal carcinoma antigen NY-REN-55, serine/threonine-protein kinase Nek1, SRPS2, SRPS2A, SRTD6. |
| NCBI Gene Id | 4750 |
| Protein Name | Serine/threonine-protein kinase Nek1 |
| Description of Target | Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity (By similarity). Involved in DNA damage checkpoint control and for proper DNA damage repair. In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death (PubMed:20230784). May be implicated in the control of meiosis (By similarity). Involved in cilium assembly (PubMed:21211617). |
| Uniprot ID | Q96PY6 |
| Protein Accession # | NP_001186326.1 |
| Nucleotide Accession # | NM_001199397.1 |
