Neurokinin 1 Receptor Polyclonal Antibody PE-Cy7 Conjugated
Référence MBS9462066-5x0,1mL
Conditionnement : 5x0.1mL
Marque : MyBiosource
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Neurokinin 1 Receptor (TACR1) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9462066MBS9462066 is an antibody targeting TACR1. Also known as Neurokinin 1 Receptor Polyclonal Antibody PE-Cy7 Conjugated. Reactive in Human, Mouse, Rat. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
Neurokinin 1 Receptor (TACR1), Polyclonal Antibody
Full Product Name
Neurokinin 1 Receptor Polyclonal Antibody PE-Cy7 Conjugated
Product Gene Name
anti-TACR1 antibody
Product Synonym Names
Neurokinin 1 Receptor
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Purity/Purification
affinity purified by Protein A
Preparation and Storage
Store at -20 degree C for one year. Avoid repeated freeze/thaw cycles.
Shipped at 4 degree C.
Shipped at 4 degree C.
Applications Tested/Suitable for anti-TACR1 antibody
Immunofluorescence (IF)
Application Notes for anti-TACR1 antibody
IF: 1:50-200
Other Notes
Small volumes of anti-TACR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for TACR1. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
substance-P receptor isoform long
NCBI Official Synonym Full Names
tachykinin receptor 1
NCBI Official Symbol
TACR1
NCBI Official Synonym Symbols
SPR; NK1R; NKIR; TAC1R
UniProt Protein Name
Substance-P receptor
UniProt Synonym Protein Names
NK-1 receptor; NK-1R; Tachykinin receptor 1
Protein Family
Substance-P receptor
UniProt Gene Name
TACR1
UniProt Synonym Gene Names
NK1R; TAC1R; SPR; NK-1R
UniProt Entry Name
NK1R_HUMAN
NCBI Protein Information
substance-P receptor; NK-1R; NK-1 receptor; tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor)
NCBI Summary for TACR1
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq, Sep 2008]
Show more UniProt Comments for TACR1
TACR1: This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2p12
Cellular Component: cell surface; integral to plasma membrane; dendrite; cytoplasm; plasma membrane
Molecular Function: protein binding; substance P receptor activity; tachykinin receptor activity
Biological Process: response to nicotine; tachykinin signaling pathway; positive regulation of leukocyte migration; response to morphine; positive regulation of saliva secretion; response to estradiol stimulus; elevation of cytosolic calcium ion concentration; behavioral response to pain; regulation of smooth muscle cell migration; positive regulation of lymphocyte proliferation; positive regulation of stress fiber formation; positive regulation of action potential; response to electrical stimulus; inflammatory response; angiotensin mediated drinking behavior; associative learning; detection of abiotic stimulus; positive regulation of synaptic transmission, cholinergic; regulation of smooth muscle cell proliferation; eating behavior; positive regulation of hormone secretion; positive regulation of synaptic transmission, GABAergic; positive regulation of ossification; positive regulation of vascular permeability; response to ethanol; long-term memory; smooth muscle contraction involved in micturition; response to heat; response to ozone; operant conditioning; positive regulation of vasoconstriction; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); sperm ejaculation; response to progesterone stimulus; positive regulation of epithelial cell proliferation; positive regulation of blood pressure; acute inflammatory response
Show more Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2p12
Cellular Component: cell surface; integral to plasma membrane; dendrite; cytoplasm; plasma membrane
Molecular Function: protein binding; substance P receptor activity; tachykinin receptor activity
Biological Process: response to nicotine; tachykinin signaling pathway; positive regulation of leukocyte migration; response to morphine; positive regulation of saliva secretion; response to estradiol stimulus; elevation of cytosolic calcium ion concentration; behavioral response to pain; regulation of smooth muscle cell migration; positive regulation of lymphocyte proliferation; positive regulation of stress fiber formation; positive regulation of action potential; response to electrical stimulus; inflammatory response; angiotensin mediated drinking behavior; associative learning; detection of abiotic stimulus; positive regulation of synaptic transmission, cholinergic; regulation of smooth muscle cell proliferation; eating behavior; positive regulation of hormone secretion; positive regulation of synaptic transmission, GABAergic; positive regulation of ossification; positive regulation of vascular permeability; response to ethanol; long-term memory; smooth muscle contraction involved in micturition; response to heat; response to ozone; operant conditioning; positive regulation of vasoconstriction; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); sperm ejaculation; response to progesterone stimulus; positive regulation of epithelial cell proliferation; positive regulation of blood pressure; acute inflammatory response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-TACR1 antibody
| Reference Product | PubMed Publications |
|---|---|
| TAC1 antibody | >22 publications with TACR1 and TAC1 |
| TAC3 antibody | >3 publications with TACR1 and TAC3 |
| GRK5 antibody | >2 publications with TACR1 and GRK5 |
Pathways associated with anti-TACR1 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Calcium Signaling Pathway antibodies | Calcium Signaling Pathway Diagram |
| Calcium Signaling Pathway antibodies | Calcium Signaling Pathway Diagram |
| Class A/1 (Rhodopsin-like Receptors) Pathway antibodies | Class A/1 (Rhodopsin-like Receptors) Pathway Diagram |
| G Alpha (q) Signalling Events Pathway antibodies | G Alpha (q) Signalling Events Pathway Diagram |
| GPCR Downstream Signaling Pathway antibodies | GPCR Downstream Signaling Pathway Diagram |
| GPCR Ligand Binding Pathway antibodies | GPCR Ligand Binding Pathway Diagram |
| Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies | Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram |
| Measles Pathway antibodies | Measles Pathway Diagram |
| Measles Pathway antibodies | Measles Pathway Diagram |
| Neuroactive Ligand-receptor Interaction Pathway antibodies | Neuroactive Ligand-receptor Interaction Pathway Diagram |
Diseases associated with anti-TACR1 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Pain Antibodies | >581 publications with TACR1 and Pain |
| Inflammation Antibodies | >523 publications with TACR1 and Inflammation |
| Vomiting Antibodies | >232 publications with TACR1 and Vomiting |
| Neoplasms Antibodies | >192 publications with TACR1 and Neoplasms |
| Neurogenic Inflammation Antibodies | >171 publications with TACR1 and Neurogenic Inflammation |
| Hyperalgesia Antibodies | >171 publications with TACR1 and Hyperalgesia |
| Brain Diseases Antibodies | >123 publications with TACR1 and Brain Diseases |
| Edema Antibodies | >105 publications with TACR1 and Edema |
| Lung Diseases Antibodies | >92 publications with TACR1 and Lung Diseases |
| Necrosis Antibodies | >76 publications with TACR1 and Necrosis |
Organs/Tissues associated with anti-TACR1 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >1184 publications with TACR1 and Brain |
| Trachea Antibodies | >129 publications with TACR1 and Trachea |
| Pancreas Antibodies | >60 publications with TACR1 and Pancreas |
| Eye Antibodies | >56 publications with TACR1 and Eye |
| Spleen Antibodies | >25 publications with TACR1 and Spleen |
| Connective Tissue Antibodies | >25 publications with TACR1 and Connective Tissue |
| Uterus Antibodies | >22 publications with TACR1 and Uterus |
| Embryonic Tissue Antibodies | >19 publications with TACR1 and Embryonic Tissue |
| Adipose Tissue Antibodies | >7 publications with TACR1 and Adipose Tissue |