OSI-930
Référence MBS3605783-10mg
Conditionnement : 10mg
Marque : MyBiosource
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OSI-930
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605783A potent, orally active, dual inhibitor of c-Kit and VEGFR-2 (KDR) with IC50 of 15 nM and 9 nM, respectively. More details
Product Overview
Online Datasheet in PDFProduct Name
OSI-930, Biochemical
Full Product Name
OSI-930
Product Synonym Names
OSI 930; OSI930
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20°C
Stability: >=2 years
Stability: >=2 years
Molecular Weight
443.44
Suitability
10mM in DMSO
Target
c-Kit
Receptor
C-Raf; CSF-1R; FLT1; Lck; VEGFR2 (KDR)
Chemical Name
2-Thiophenecarboxamide, 3-[(4-quinolinylmethyl)amino]-N-[4-(trifluoromethoxy)phenyl]
SMILES
O=C(C1=C(NCC2=CC=NC3=CC=CC=C23)C=CS1)NC4=CC=C(OC(F)(F)F)C=C4
Molecular Formula
C22H16F3N3O2S
CAS Number
728033-96-3
Pathway
Angiogenesis
Product Categories/Family for OSI-930 biochemical
Solid Tumors; Angiogenesis; Cancer
Product References and Citations for OSI-930 biochemical
1. Garton AJ, et al. Cancer Res. 2006 Jan 15; 66 (2):1015-24.
2. Yap TA, et al. Clin Cancer Res. 2013 Feb 15; 19 (4):909-19.
3. Patel JP, et al. Bioorg Med Chem Lett. 2011 Nov 1; 21 (21):6495-9.
4. Macpherson IR, et al. Eur J Cancer. 2013 Mar; 49 (4):782-9.
2. Yap TA, et al. Clin Cancer Res. 2013 Feb 15; 19 (4):909-19.
3. Patel JP, et al. Bioorg Med Chem Lett. 2011 Nov 1; 21 (21):6495-9.
4. Macpherson IR, et al. Eur J Cancer. 2013 Mar; 49 (4):782-9.
Other Notes
Small volumes of OSI-930 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for OSI-930 purchase
MBS3605783 is a biochemical targeting OSI-930.
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