OVA Conjugated Thyrotropin Releasing Hormone (TRH)
Référence MBS2086305-5x5mg
Conditionnement : 5x5mg
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TRH Small Molecule – Thyrotropin Releasing Hormone
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2086305SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2086305 is a small molecule targeting TRH. Also known as OVA Conjugated Thyrotropin Releasing Hormone (TRH). Host: Protein Conjugation. More details
Product Overview
Product Name
Thyrotropin Releasing Hormone (TRH), Small Molecule
Full Product Name
OVA Conjugated Thyrotropin Releasing Hormone (TRH)
Product Gene Name
TRH small molecule
Product Synonym Names
TRF; Thyrotropin-Releasing Factor; Thyroliberin; Protirelin; Pro-tirelin; Prothyroliberin; TSH-releasing factor
Host
Protein Conjugation
Form/Format
Freeze-dried powder
Purity/Purification
> 90%
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Molecular Weight
27,404 Da
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Buffer Formulation
PBS, pH7.4.
Organism Species
Human
Usage
Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Product Categories/Family for TRH small molecule
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for TRH small molecule
Immunogen, SDS-PAGE, Western Blot (WB)
Other Notes
Small volumes of TRH small molecule vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for TRH. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
thyrotropin releasing hormone preproprotein
NCBI Official Synonym Full Names
thyrotropin releasing hormone
NCBI Official Symbol
TRH
NCBI Official Synonym Symbols
TRF; Pro-TRH
UniProt Protein Name
Pro-thyrotropin-releasing hormone
UniProt Synonym Protein Names
Prothyroliberin
Protein Family
Pro-thyrotropin-releasing hormone
UniProt Gene Name
TRH
UniProt Synonym Gene Names
Pro-TRH; TRH; TRF
NCBI Protein Information
thyrotropin releasing hormone
NCBI Summary for TRH
This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013]
Show more UniProt Comments for TRH
TRH: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. May promote hair shaft elongation, prolonge the hair cycle growth phase (anagen) and antagonized its termination by TGFB2. May also increase proliferation and inhibited apoptosis of hair matrix keratinocytes. Belongs to the TRH family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 3q22.1
Cellular Component: extracellular region; nucleus; plasma membrane; secretory granule
Biological Process: cell-cell signaling; eating behavior; histamine metabolic process; negative regulation of glutamate secretion; positive regulation of gamma-aminobutyric acid secretion; positive regulation of insulin secretion; signal transduction
Disease: Thyrotropin-releasing Hormone Deficiency
Show more Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 3q22.1
Cellular Component: extracellular region; nucleus; plasma membrane; secretory granule
Biological Process: cell-cell signaling; eating behavior; histamine metabolic process; negative regulation of glutamate secretion; positive regulation of gamma-aminobutyric acid secretion; positive regulation of insulin secretion; signal transduction
Disease: Thyrotropin-releasing Hormone Deficiency
Research Articles on TRH
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with TRH small molecule
| Reference Product | PubMed Publications |
|---|---|
| PRL small molecule | >1751 publications with TRH and PRL |
| GHRH small molecule | >246 publications with TRH and GHRH |
| CCK small molecule | >62 publications with TRH and CCK |
| TRHR small molecule | >47 publications with TRH and TRHR |
| NTS small molecule | >14 publications with TRH and NTS |
| GRP small molecule | >8 publications with TRH and GRP |
| GCG small molecule | >2 publications with TRH and GCG |
| GNRH1 small molecule | >1 publications with TRH and GNRH1 |
Pathways associated with TRH small molecule
| Products by Pathway | Pathway Diagram |
|---|---|
| Class A/1 (Rhodopsin-like Receptors) Pathway antibodies | Class A/1 (Rhodopsin-like Receptors) Pathway Diagram |
| G Alpha (q) Signalling Events Pathway antibodies | G Alpha (q) Signalling Events Pathway Diagram |
| GPCR Downstream Signaling Pathway antibodies | GPCR Downstream Signaling Pathway Diagram |
| GPCR Ligand Binding Pathway antibodies | GPCR Ligand Binding Pathway Diagram |
| Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies | Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram |
| Peptide Ligand-binding Receptors Pathway antibodies | Peptide Ligand-binding Receptors Pathway Diagram |
| Signal Transduction Pathway antibodies | Signal Transduction Pathway Diagram |
| Signaling By GPCR Pathway antibodies | Signaling By GPCR Pathway Diagram |
Diseases associated with TRH small molecule
| Disease Name | Pubmed Publications |
|---|---|
| Nervous System Diseases Antibodies | >1987 publications with TRH and Nervous System Diseases |
| Brain Diseases Antibodies | >1675 publications with TRH and Brain Diseases |
| THYROTROPIN-RELEASING HORMONE DEFICIENCY Antibodies | >282 publications with TRH and THYROTROPIN-RELEASING HORMONE DEFICIENCY |
| Disease Models, Animal Antibodies | >130 publications with TRH and Disease Models, Animal |
| Drug Toxicity Antibodies | >108 publications with TRH and Drug Toxicity |
| Bipolar Disorder Antibodies | >102 publications with TRH and Bipolar Disorder |
| Seizures Antibodies | >94 publications with TRH and Seizures |
| Hypothermia Antibodies | >91 publications with TRH and Hypothermia |
| Hypertension Antibodies | >87 publications with TRH and Hypertension |
| Pain Antibodies | >83 publications with TRH and Pain |
Organs/Tissues associated with TRH small molecule
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >4618 publications with TRH and Brain |
| Ovary Antibodies | >123 publications with TRH and Ovary |
| Lung Antibodies | >111 publications with TRH and Lung |
| Eye Antibodies | >109 publications with TRH and Eye |
| Pineal Gland Antibodies | >48 publications with TRH and Pineal Gland |
| Bone Marrow Antibodies | >12 publications with TRH and Bone Marrow |
| Cervix Antibodies | >3 publications with TRH and Cervix |
| Uncharacterized Tissue Antibodies | >1 publications with TRH and Uncharacterized Tissue |