PAX7 Antibody - C-terminal region
Référence ARP32742_P050
Conditionnement : 100ul
Marque : Aviva Systems Biology
PAX7 Antibody - C-terminal region (ARP32742_P050)
| Datasheets/Manuals | Printable datasheet for anti-PAX7 (ARP32742_P050) antibody |
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| Publications | Effects of 4-Aminopyridine on Combined Nerve and Muscle Injury and Bone Loss Authors: Govindappa, P. K., Jagadeeshaprasad, M. G., et al. Journal: J Hand Surg Am. 48, 831.e1-831.e9 (2023) The vascularization, innervation and myogenesis of early regenerated tail in Gekko japonicus Authors: Liu, Z., Huang, S., et al. Journal: J Mol Histol. 52, 1189-1204 (2021) The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts Authors: Venugopal, N., Ghosh, A., et al. Journal: BMC Mol Cell Biol. 21, 25 (2020) The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts Authors: Venugopal, N., Ghosh, A., et al. Journal: Research Square. (2020) Preprint — no PubMed record available The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts Authors: Venugopal, N., Ghosh, A., et al. Journal: bioRxiv. (2019) Preprint — no PubMed record available PAX3 Confers Functional Heterogeneity in Skeletal Muscle Stem Cell Responses to Environmental Stress Authors: Der Vartanian, A., Quétin, M., et al. Journal: Cell Stem Cell. 24, 958-973.e9 (2019) The role of Pitx2 and Pitx3 in muscle stem cells gives new insights into P38α MAP kinase and redox regulation of muscle regeneration Authors: L'honoré, A., Commere, P. H., et al. Journal: Elife. 7 (2018) First Neuromuscular Contact Correlates with Onset of Primary Myogenesis in Rat and Mouse Limb Muscles Authors: Hurren, B., Collins, J. J., et al. Journal: PLoS One. 10, e0133811 (2015) Embryonic founders of adult muscle stem cells are primed by the determination gene Mrf4 Authors: Sambasivan, R., Comai, G., et al. Journal: Dev Biol. 381, 241-55 (2013) Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration Authors: Sambasivan, R., Yao, R., et al. Journal: Development. 138, 3647-56 (2011) |
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| Tested Species Reactivity | Human |
| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | IHC, WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the C-terminal region of PAX7 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93% |
| Peptide Sequence | Synthetic peptide located within the following region: QADFSISPLHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTT |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-PAX7 (ARP32742_P050) antibody is Catalog # AAP32742 |
| Gene Symbol | PAX7 |
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| Gene Full Name | Paired box 7 |
| Alias Symbols | HUP1, RMS2, PAX7B, MYOSCO |
| NCBI Gene Id | 5081 |
| Protein Name | Paired box protein Pax-7 |
| Description of Target | PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box gene 7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown. |
| Uniprot ID | P23759 |
| Protein Accession # | NP_002575 |
| Nucleotide Accession # | NM_002584 |
| Protein Size (# AA) | 520 |
| Molecular Weight | 57kDa |
| Protein Interactions | TRIM27; MYOD1; Dlg4; WDR5; ASH2L; HIRA; Ubc; |
| Name | # of Products |
|---|---|
| ASH2L | 81 |
| HIRA | 40 |
| Ubc | 7030 |
| WDR5 | 91 |
| Name | # of Products |
|---|---|
| Anti-apoptosis | 727 |
| Transcription, DNA-dependent | 3394 |
| Name | # of Products |
|---|---|
| Anatomical structure morphogenesis | 88 |
| Anti-apoptosis | 239 |
| Cartilage development | 76 |
| Dorsal/ventral neural tube patterning | 19 |
| Embryonic skeletal system development | 48 |
| Multicellular organismal development | 896 |
| Muscle tissue morphogenesis | 6 |
| Neuron fate commitment | 25 |
| Regulation of transcription, DNA-dependent | 1734 |
| Satellite cell commitment | 3 |
| Skeletal muscle tissue development | 53 |
| Skeletal muscle tissue regeneration | 12 |
| Spinal cord association neuron differentiation | 15 |
| Name | # of Products |
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| Nucleus | 4914 |
| Name | # of Products |
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| Sequence-specific DNA binding | 1803 |
| Sequence-specific DNA binding transcription factor activity | 2776 |
| Name | # of Products |
|---|---|
| Proto-oncogene | 793 |
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