PD-1 Polyclonal Antibody PE-Cy5 Conjugated
Référence MBS9463092-5x0,1mL
Conditionnement : 5x0.1mL
Marque : MyBiosource
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PD-1 Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9463092MBS9463092 is an antibody targeting PD-1. Also known as PD-1 Polyclonal Antibody PE-Cy5 Conjugated. Reactive in Human, Mouse, Rat. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
PD-1, Polyclonal Antibody
Full Product Name
PD-1 Polyclonal Antibody PE-Cy5 Conjugated
Product Gene Name
anti-PD-1 antibody
Product Synonym Names
PD-1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Purity/Purification
affinity purified by Protein A
Preparation and Storage
Store at -20 degree C for one year. Avoid repeated freeze/thaw cycles.
Shipped at 4 degree C.
Shipped at 4 degree C.
Applications Tested/Suitable for anti-PD-1 antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF)
Application Notes for anti-PD-1 antibody
FC/FACS: 1:50-200
IF: 1:50-200
IF: 1:50-200
Other Notes
Small volumes of anti-PD-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for PD-1. It may not necessarily be applicable to this product.
NCBI Official Full Name
Programmed cell death protein 1
NCBI Official Synonym Full Names
programmed cell death 1
NCBI Official Symbol
PDCD1
NCBI Official Synonym Symbols
PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1
UniProt Protein Name
Programmed cell death protein 1
UniProt Synonym Protein Names
CD_antigen: CD279
UniProt Gene Name
PDCD1
UniProt Synonym Gene Names
PD1; Protein PD-1; hPD-1
NCBI Protein Information
programmed cell death protein 1
NCBI Summary for PD-1
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for PD-1
Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-PD-1 antibody
| Reference Product | PubMed Publications |
|---|---|
| CD4 antibody | >415 publications with PD-1 and CD4 |
| CD274 antibody | >332 publications with PD-1 and CD274 |
| PDCD1LG2 antibody | >98 publications with PD-1 and PDCD1LG2 |
| PTPN6 antibody | >7 publications with PD-1 and PTPN6 |
| PTPN11 antibody | >7 publications with PD-1 and PTPN11 |
| HLA-DR4 antibody | >1 publications with PD-1 and HLA-DR4 |
Pathways associated with anti-PD-1 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Adaptive Immune System Pathway antibodies | Adaptive Immune System Pathway Diagram |
| Cell Adhesion Molecules (CAMs) Pathway antibodies | Cell Adhesion Molecules (CAMs) Pathway Diagram |
| Cell Adhesion Molecules (CAMs) Pathway antibodies | Cell Adhesion Molecules (CAMs) Pathway Diagram |
| Costimulation By The CD28 Family Pathway antibodies | Costimulation By The CD28 Family Pathway Diagram |
| Immune System Pathway antibodies | Immune System Pathway Diagram |
| PD-1 Signaling Pathway antibodies | PD-1 Signaling Pathway Diagram |
| T Cell Receptor Signaling Pathway antibodies | T Cell Receptor Signaling Pathway Diagram |
| T Cell Receptor Signaling Pathway antibodies | T Cell Receptor Signaling Pathway Diagram |
Diseases associated with anti-PD-1 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Liver Diseases Antibodies | >146 publications with PD-1 and Liver Diseases |
| Inflammation Antibodies | >115 publications with PD-1 and Inflammation |
| Melanoma Antibodies | >76 publications with PD-1 and Melanoma |
| Necrosis Antibodies | >74 publications with PD-1 and Necrosis |
| Lupus Erythematosus, Systemic Antibodies | >72 publications with PD-1 and Lupus Erythematosus, Systemic |
| Lung Diseases Antibodies | >58 publications with PD-1 and Lung Diseases |
| Lung Neoplasms Antibodies | >38 publications with PD-1 and Lung Neoplasms |
| Adenocarcinoma Antibodies | >35 publications with PD-1 and Adenocarcinoma |
| Kidney Diseases Antibodies | >28 publications with PD-1 and Kidney Diseases |
| Liver Neoplasms Antibodies | >26 publications with PD-1 and Liver Neoplasms |
Organs/Tissues associated with anti-PD-1 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >937 publications with PD-1 and Blood |
| Kidney Antibodies | >36 publications with PD-1 and Kidney |