PE-Linked Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 2 (CXCL2)
Référence MBS2118611-0,2mL
Conditionnement : 0.2mL
Marque : MyBiosource
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Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2118611SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2118611 is an antibody targeting CXCL2. Also known as PE-Linked Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 2 (CXCL2). Reactive in Horse. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
Chemokine (C-X-C Motif) Ligand 2 (CXCL2), Polyclonal Antibody
Full Product Name
PE-Linked Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 2 (CXCL2)
Product Gene Name
anti-CXCL2 antibody
Product Synonym Names
GROb; SCYB2; MIP2; GRO2; MIP2a; MGSAb; CINC2a; HSF; Macrophage inflammatory protein 2-alpha; Hematopoietic synergistic factor; Growth Regulated Oncogene Beta
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Horse
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
>=100ug/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against CXCL2. It has been selected for its ability to recognize CXCL2 in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: CXCL2 (MBS2112121)
PE Conjugated Antibody: CXCL2 (MBS2118611)
PE Conjugated Antibody: CXCL2 (MBS2118611)
OMIM
139110
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Cross Reactivity
Horse
Conjugation
PE
Product Categories/Family for anti-CXCL2 antibody
Cytokine; Tumor Immunity; Infection Immunity
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-CXCL2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Other Notes
Small volumes of anti-CXCL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for CXCL2. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
C-X-C motif chemokine 2
NCBI Official Synonym Full Names
C-X-C motif chemokine ligand 2
NCBI Official Symbol
CXCL2
NCBI Official Synonym Symbols
GRO2; GROb; MIP2; MIP2A; SCYB2; MGSA-b; MIP-2a; CINC-2a
UniProt Protein Name
C-X-C motif chemokine 2
UniProt Synonym Protein Names
Growth-regulated protein beta; Gro-beta; Macrophage inflammatory protein 2-alpha; MIP2-alphaCleaved into the following chain:GRO-beta(5-73); Alternative name(s):; GRO-beta-T; Hematopoietic synergistic factor; HSF; SB-251353
Protein Family
C-X-C motif chemokine
UniProt Gene Name
CXCL2
UniProt Synonym Gene Names
GRO2; GROB; MIP2A; SCYB2; Gro-beta; MIP2-alpha; HSF
UniProt Entry Name
CXCL2_HUMAN
NCBI Protein Information
C-X-C motif chemokine 2
NCBI Summary for CXCL2
This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation. [provided by RefSeq, Sep 2014]
Show more UniProt Comments for CXCL2
CXCL2: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted
Chromosomal Location of Human Ortholog: 4q21
Cellular Component: extracellular space; extracellular region
Molecular Function: protein binding; chemokine activity; CXCR chemokine receptor binding
Biological Process: G-protein coupled receptor protein signaling pathway; response to molecule of bacterial origin; response to lipopolysaccharide; immune response; positive regulation of leukocyte chemotaxis; chemotaxis; inflammatory response; regulation of cell proliferation
Show more Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted
Chromosomal Location of Human Ortholog: 4q21
Cellular Component: extracellular space; extracellular region
Molecular Function: protein binding; chemokine activity; CXCR chemokine receptor binding
Biological Process: G-protein coupled receptor protein signaling pathway; response to molecule of bacterial origin; response to lipopolysaccharide; immune response; positive regulation of leukocyte chemotaxis; chemotaxis; inflammatory response; regulation of cell proliferation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-CXCL2 antibody
| Reference Product | PubMed Publications |
|---|---|
| CXCL1 antibody | >569 publications with CXCL2 and CXCL1 |
| CCL4 antibody | >188 publications with CXCL2 and CCL4 |
| CXCR2 antibody | >153 publications with CXCL2 and CXCR2 |
| CCL5 antibody | >127 publications with CXCL2 and CCL5 |
| CXCL3 antibody | >100 publications with CXCL2 and CXCL3 |
| CCL20 antibody | >78 publications with CXCL2 and CCL20 |
| CCR1 antibody | >26 publications with CXCL2 and CCR1 |
| CXCR1 antibody | >25 publications with CXCL2 and CXCR1 |
| CCR5 antibody | >23 publications with CXCL2 and CCR5 |
| CCL19 antibody | >7 publications with CXCL2 and CCL19 |
Pathways associated with anti-CXCL2 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Chemokine Receptors Bind Chemokines Pathway antibodies | Chemokine Receptors Bind Chemokines Pathway Diagram |
| Chemokine Signaling Pathway antibodies | Chemokine Signaling Pathway Diagram |
| Chemokine Signaling Pathway antibodies | Chemokine Signaling Pathway Diagram |
| Class A/1 (Rhodopsin-like Receptors) Pathway antibodies | Class A/1 (Rhodopsin-like Receptors) Pathway Diagram |
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
| Cytokines And Inflammatory Response Pathway antibodies | Cytokines And Inflammatory Response Pathway Diagram |
| Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies | Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram |
| Disease Pathway antibodies | Disease Pathway Diagram |
| G Alpha (i) Signalling Events Pathway antibodies | G Alpha (i) Signalling Events Pathway Diagram |
Diseases associated with anti-CXCL2 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Inflammation Antibodies | >1033 publications with CXCL2 and Inflammation |
| Necrosis Antibodies | >652 publications with CXCL2 and Necrosis |
| Lung Diseases Antibodies | >391 publications with CXCL2 and Lung Diseases |
| Disease Models, Animal Antibodies | >366 publications with CXCL2 and Disease Models, Animal |
| Lung Injury Antibodies | >265 publications with CXCL2 and Lung Injury |
| Pneumonia Antibodies | >175 publications with CXCL2 and Pneumonia |
| Reperfusion Injury Antibodies | >115 publications with CXCL2 and Reperfusion Injury |
| Wounds and Injuries Antibodies | >98 publications with CXCL2 and Wounds and Injuries |
| Edema Antibodies | >96 publications with CXCL2 and Edema |
| Skin Diseases Antibodies | >84 publications with CXCL2 and Skin Diseases |
Organs/Tissues associated with anti-CXCL2 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >1077 publications with CXCL2 and Blood |
| Lung Antibodies | >637 publications with CXCL2 and Lung |
| Liver Antibodies | >206 publications with CXCL2 and Liver |
| Bone Antibodies | >171 publications with CXCL2 and Bone |
| Bone Marrow Antibodies | >141 publications with CXCL2 and Bone Marrow |
| Brain Antibodies | >124 publications with CXCL2 and Brain |
| Intestine Antibodies | >117 publications with CXCL2 and Intestine |
| Kidney Antibodies | >98 publications with CXCL2 and Kidney |
| Eye Antibodies | >57 publications with CXCL2 and Eye |
| Pancreas Antibodies | >43 publications with CXCL2 and Pancreas |