PE-Linked Polyclonal Antibody to Lamin B1 (LMNB1)
Référence MBS2076766-5x5mL
Conditionnement : 5x5mL
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Lamin B1 (LMNB1) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2076766SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2076766 is an antibody targeting LMNB1. Also known as PE-Linked Polyclonal Antibody to Lamin B1 (LMNB1). Reactive in Human, Mouse, Rat, Dog, Pig, Bovine, Goat, Horse. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
Lamin B1 (LMNB1), Polyclonal Antibody
Full Product Name
PE-Linked Polyclonal Antibody to Lamin B1 (LMNB1)
Product Gene Name
anti-LMNB1 antibody
Product Synonym Names
LMN; LMN2; LMNB
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Dog, Pig, Bovine, Goat, Horse
Concentration
>=100ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: LMNB1 (MBS2027031)
PE Conjugated Antibody: LMNB1 (MBS2076766)
PE Conjugated Antibody: LMNB1 (MBS2076766)
Matching Pairs
PE Conjugated Antibody: LMNB1 (MBS2076766)
Immunogen: LMNB1 (MBS2031124)
Immunogen: LMNB1 (MBS2031124)
Molecular Weight
66,408 Da
OMIM
M34458 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
LMNB1 (Ser52~Gly233)
Conjugation
PE
Cross Reactivity
Human, Pig
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2027031
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-LMNB1 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)
Other Notes
Small volumes of anti-LMNB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for LMNB1. It may not necessarily be applicable to this product.
NCBI Official Full Name
lamin B1
NCBI Official Synonym Full Names
lamin B1
NCBI Official Symbol
LMNB1
NCBI Official Synonym Symbols
LMN; ADLD; LMN2; LMNB
UniProt Protein Name
Lamin-B1
Protein Family
Lamin
UniProt Gene Name
LMNB1
UniProt Synonym Gene Names
LMN2; LMNB
NCBI Protein Information
lamin-B1
NCBI Summary for LMNB1
This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
UniProt Comments for LMNB1
Lamin B1: nuclear lamins are intermediate filament proteins that constitute the lattice-like matrix at the inner face of the nuclear membrane that underlies the nuclear envelop. The lamins, highly conserved throughout evolution, are encoded by three genes in the human: LMNA, LMNB1, and LMNB2. The A-type lamins (lamin A/C) are developmentally regulated and are generally expressed in differentiated cells. The anchoring of chromatin to the nuclear lamina is involved in the control of gene expression and in DNA replication and repair. During mitosis, the nuclear lamina is reversibly disassembled as the lamin proteins are phosphorylated. B-type lamins are phosphorylated within minutes of engaging the IgM surface receptor of resting splenic B cells. Nuclear lamins are cleaved by caspases during apoptosis.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 5q23.2
Cellular Component: membrane; nuclear envelope; nuclear membrane; nucleoplasm
Molecular Function: protein binding
Disease: Leukodystrophy, Demyelinating, Adult-onset, Autosomal Dominant
Show more Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 5q23.2
Cellular Component: membrane; nuclear envelope; nuclear membrane; nucleoplasm
Molecular Function: protein binding
Disease: Leukodystrophy, Demyelinating, Adult-onset, Autosomal Dominant
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-LMNB1 antibody
| Reference Product | PubMed Publications |
|---|---|
| LMNA antibody | >16 publications with LMNB1 and LMNA |
| SYNE1 antibody | >1 publications with LMNB1 and SYNE1 |
| CDK1 antibody | >1 publications with LMNB1 and CDK1 |
Pathways associated with anti-LMNB1 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Apoptosis Pathway antibodies | Apoptosis Pathway Diagram |
| Apoptotic Cleavage Of Cellular Proteins Pathway antibodies | Apoptotic Cleavage Of Cellular Proteins Pathway Diagram |
| Apoptotic Execution Phase Pathway antibodies | Apoptotic Execution Phase Pathway Diagram |
| Breakdown Of The Nuclear Lamina Pathway antibodies | Breakdown Of The Nuclear Lamina Pathway Diagram |
| Caspase Cascade In Apoptosis Pathway antibodies | Caspase Cascade In Apoptosis Pathway Diagram |
| Cell Cycle Pathway antibodies | Cell Cycle Pathway Diagram |
| Cell Cycle, Mitotic Pathway antibodies | Cell Cycle, Mitotic Pathway Diagram |
| Cellular Senescence Pathway antibodies | Cellular Senescence Pathway Diagram |
| Cellular Responses To Stress Pathway antibodies | Cellular Responses To Stress Pathway Diagram |
| DNA Damage/Telomere Stress Induced Senescence Pathway antibodies | DNA Damage/Telomere Stress Induced Senescence Pathway Diagram |
Diseases associated with anti-LMNB1 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Nervous System Diseases Antibodies | >22 publications with LMNB1 and Nervous System Diseases |
| Liver Diseases Antibodies | >4 publications with LMNB1 and Liver Diseases |
| Pelizaeus-Merzbacher Disease Antibodies | >4 publications with LMNB1 and Pelizaeus-Merzbacher Disease |
| Liver Neoplasms Antibodies | >3 publications with LMNB1 and Liver Neoplasms |
| Carcinoma, Hepatocellular Antibodies | >3 publications with LMNB1 and Carcinoma, Hepatocellular |
| Disease Models, Animal Antibodies | >2 publications with LMNB1 and Disease Models, Animal |
| Neoplasm Metastasis Antibodies | >1 publications with LMNB1 and Neoplasm Metastasis |
| Pancreatic Neoplasms Antibodies | >1 publications with LMNB1 and Pancreatic Neoplasms |
| Kidney Diseases Antibodies | >1 publications with LMNB1 and Kidney Diseases |
| Inflammation Antibodies | >1 publications with LMNB1 and Inflammation |
Organs/Tissues associated with anti-LMNB1 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >15 publications with LMNB1 and Brain |
| Blood Antibodies | >9 publications with LMNB1 and Blood |
| Skin Antibodies | >6 publications with LMNB1 and Skin |
| Muscle Antibodies | >5 publications with LMNB1 and Muscle |
| Liver Antibodies | >4 publications with LMNB1 and Liver |
| Bone Antibodies | >4 publications with LMNB1 and Bone |
| Pancreas Antibodies | >1 publications with LMNB1 and Pancreas |
| Lung Antibodies | >1 publications with LMNB1 and Lung |
| Intestine Antibodies | >1 publications with LMNB1 and Intestine |
| Connective Tissue Antibodies | >1 publications with LMNB1 and Connective Tissue |