Polyclonal Antibody to Interleukin 1 Alpha (IL1a)

Référence MBS2003462-0,1mL

Conditionnement : 0.1mL

Marque : MyBiosource

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Interleukin 1 Alpha (IL1a) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2003462
SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2003462 is an antibody targeting IL1a. Also known as Polyclonal Antibody to Interleukin 1 Alpha (IL1a). Reactive in Horse. Host: Rabbit. More details

Product Overview

Online Datasheet in PDF
Product Name
Interleukin 1 Alpha (IL1a), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Interleukin 1 Alpha (IL1a)
Product Gene Name
anti-IL1a antibody
Immunogen Sequence
Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSG SEF- DDLEAI ANDPEEGIIR PRSVHYNFQS NTKYNFMRIV NHQCTLNDAL NQSVIRDTSG QYLATAALNN LDDAVKFDMG AYTSEEDSQL PVTLRISKTR LFVSAQNEDE PVLLKEMPDT PKTIKDETNL LFFWERHGSK NYFKSVAHPK LFIATKQGKL VHMARGQPSI TDFQILDNQ
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Horse
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
1mg/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against IL1a. It has been selected for its ability to recognize IL1a in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: IL1a (MBS2003462)
Biotin Conjugated Antibody: IL1a (MBS2004280)
Matching Pairs
Unconjugated Antibody: IL1a (MBS2003462)
Immunogen: IL1a (MBS2012076)
Molecular Weight
30,807 Da
3D Structure
ModBase 3D Structure for Q28385
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
Recombinant IL1a (Asp95~Gln269) expressed in E.coli.
Cross Reactivity
Horse
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2036765
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-IL1a antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-IL1a antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-IL1a antibody

Western Blot: Sample: Recombinant protein.
Rabbit Anti-IL1a Polyclonal Antibody – Cat# MBS2003462

Other Notes

Small volumes of anti-IL1a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL1a. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-1 alpha
NCBI Official Symbol
IL1A
UniProt Protein Name
Interleukin-1 alpha
Protein Family
Interleukin
UniProt Gene Name
IL1A
UniProt Synonym Gene Names
IL-1 alpha
NCBI Protein Information
interleukin-1 alpha

UniProt Comments for IL1a

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IL1a antibody

 Reference Product  PubMed Publications
 IL6 antibody  >129 publications with IL1a and IL6
 IL1RN antibody  >112 publications with IL1a and IL1RN
 TGFB1 antibody  >23 publications with IL1a and TGFB1
 IL1R1 antibody  >16 publications with IL1a and IL1R1
 GM-CSF antibody  >11 publications with IL1a and GM-CSF
 TIMP1 antibody  >2 publications with IL1a and TIMP1
 VCAM antibody  >1 publications with IL1a and VCAM
 IL1RAP antibody  >1 publications with IL1a and IL1RAP
 IL-1RII antibody  >1 publications with IL1a and IL-1RII

Pathways associated with anti-IL1a antibody

 Products by Pathway  Pathway Diagram
 AGE-RAGE Signaling Pathway In Diabetic Complications antibodies  AGE-RAGE Signaling Pathway In Diabetic Complications Diagram
 AGE-RAGE Signaling Pathway In Diabetic Complications antibodies  AGE-RAGE Signaling Pathway In Diabetic Complications Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Graft-versus-host Disease Pathway antibodies  Graft-versus-host Disease Pathway Diagram
 Graft-versus-host Disease Pathway antibodies  Graft-versus-host Disease Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Inflammatory Bowel Disease (IBD) Pathway antibodies  Inflammatory Bowel Disease (IBD) Pathway Diagram
 Inflammatory Bowel Disease (IBD) Pathway antibodies  Inflammatory Bowel Disease (IBD) Pathway Diagram

Diseases associated with anti-IL1a antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >136 publications with IL1a and Inflammation
 Necrosis Antibodies  >80 publications with IL1a and Necrosis
 Skin Diseases Antibodies  >39 publications with IL1a and Skin Diseases
 Pain Antibodies  >13 publications with IL1a and Pain
 Heart Diseases Antibodies  >13 publications with IL1a and Heart Diseases
 Liver Diseases Antibodies  >11 publications with IL1a and Liver Diseases
 Fibrosis Antibodies  >11 publications with IL1a and Fibrosis
 Kidney Diseases Antibodies  >10 publications with IL1a and Kidney Diseases
 Myocardial Ischemia Antibodies  >9 publications with IL1a and Myocardial Ischemia
 Hypertension Antibodies  >7 publications with IL1a and Hypertension

Organs/Tissues associated with anti-IL1a antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >102 publications with IL1a and Blood