Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type Z (PTPRZ)
Référence MBS2033721-0,1mL
Conditionnement : 0.1mL
Marque : MyBiosource
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Western Blot: Sample: Human A549 cell lysate; Primary Ab: 2ug/ml Rabbit Anti-Mouse PTPRZ Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
Western Blot: Recombinant PTPRZ, Mouse.
DAB staining on fromalin fixed paraffin- embedded brain tissue)
Protein Tyrosine Phosphatase Receptor Type Z (PTPRZ) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2033721SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2033721 is an antibody targeting PTPRZ. Also known as Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type Z (PTPRZ). Reactive in Mouse, Human, Rat. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
Protein Tyrosine Phosphatase Receptor Type Z (PTPRZ), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type Z (PTPRZ)
Product Gene Name
anti-PTPRZ antibody
Product Synonym Names
PTPRZ1; HPTPZ; HPTPzeta; PTP18; PTPR-Z; PTPZ; RPTPB; RPTPbeta; Phosphacan; Receptor-type tyrosine-protein phosphatase zeta
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, Human, Rat
Form/Format
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
0.91mg/ml (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.
Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.
Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: PTPRZ (MBS2033721)
Immunogen: PTPRZ (MBS2034384)
Immunogen: PTPRZ (MBS2034384)
Matching Pairs
Unconjugated Antibody: PTPRZ (MBS2033721)
APC-CY7 Conjugated Antibody: PTPRZ (MBS2072055)
APC-CY7 Conjugated Antibody: PTPRZ (MBS2072055)
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Polyclonal antibody preparation
Traits
Liquid
Cross Reactivity
Human; Rat
Immunogen
Recombinant PTPRZ (Leu32~Phe163) expressed in E.coli (MBS2034384).
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-PTPRZ antibody
Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP).
Application Notes for anti-PTPRZ antibody
Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Other Notes
Small volumes of anti-PTPRZ antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for PTPRZ. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
receptor-type tyrosine-protein phosphatase zeta isoform 3
NCBI Official Synonym Full Names
protein tyrosine phosphatase, receptor type Z, polypeptide 1
NCBI Official Symbol
Ptprz1
NCBI Official Synonym Symbols
Ptpz; Ptprz; RPTPz; PTPbeta; PTPzeta; AI850339; DSD-1-PG; Rptpbeta; R-PTP-zeta
UniProt Protein Name
Receptor-type tyrosine-protein phosphatase zeta
UniProt Gene Name
Ptprz1
UniProt Synonym Gene Names
R-PTP-zeta
NCBI Protein Information
receptor-type tyrosine-protein phosphatase zeta
UniProt Comments for PTPRZ
PTPRZ1: May be involved in the regulation of specific developmental processes in the CNS. Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine
Chromosomal Location of Human Ortholog: 6|6 A3.1
Cellular Component: axon; cell soma; cytoplasm; dendrite; dendritic spine; extracellular region; extracellular space; filopodium; growth cone; integral component of membrane; intrinsic component of plasma membrane; lamellipodium; membrane; plasma membrane; postsynaptic membrane; proteinaceous extracellular matrix
Molecular Function: fibroblast growth factor binding; hydrolase activity; phosphoprotein phosphatase activity; phosphoric monoester hydrolase activity; protein binding; protein tyrosine phosphatase activity
Biological Process: axonal fasciculation; axonogenesis; dephosphorylation; hemopoietic progenitor cell differentiation; learning and/or memory; negative regulation of cell proliferation; oligodendrocyte differentiation; positive regulation of cell migration; positive regulation of fibroblast proliferation; positive regulation of peptidyl-tyrosine phosphorylation; protein amino acid dephosphorylation; regulation of dendrite morphogenesis
Show more Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine
Chromosomal Location of Human Ortholog: 6|6 A3.1
Cellular Component: axon; cell soma; cytoplasm; dendrite; dendritic spine; extracellular region; extracellular space; filopodium; growth cone; integral component of membrane; intrinsic component of plasma membrane; lamellipodium; membrane; plasma membrane; postsynaptic membrane; proteinaceous extracellular matrix
Molecular Function: fibroblast growth factor binding; hydrolase activity; phosphoprotein phosphatase activity; phosphoric monoester hydrolase activity; protein binding; protein tyrosine phosphatase activity
Biological Process: axonal fasciculation; axonogenesis; dephosphorylation; hemopoietic progenitor cell differentiation; learning and/or memory; negative regulation of cell proliferation; oligodendrocyte differentiation; positive regulation of cell migration; positive regulation of fibroblast proliferation; positive regulation of peptidyl-tyrosine phosphorylation; protein amino acid dephosphorylation; regulation of dendrite morphogenesis
Research Articles on PTPRZ
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-PTPRZ antibody
| Reference Product | PubMed Publications |
|---|---|
| Ptn antibody | >20 publications with PTPRZ and Ptn |
| Erbb4 antibody | >4 publications with PTPRZ and Erbb4 |
| Cntn2 antibody | >2 publications with PTPRZ and Cntn2 |
| Cntn1 antibody | >2 publications with PTPRZ and Cntn1 |
| Tnc antibody | >1 publications with PTPRZ and Tnc |
| Magi1 antibody | >1 publications with PTPRZ and Magi1 |
Pathways associated with anti-PTPRZ antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Spinal Cord Injury Pathway antibodies | Spinal Cord Injury Pathway Diagram |
Diseases associated with anti-PTPRZ antibody
| Disease Name | Pubmed Publications |
|---|---|
| Nervous System Diseases Antibodies | >40 publications with PTPRZ and Nervous System Diseases |
| Brain Diseases Antibodies | >31 publications with PTPRZ and Brain Diseases |
| Mental Disorders Antibodies | >6 publications with PTPRZ and Mental Disorders |
| Nerve Degeneration Antibodies | >5 publications with PTPRZ and Nerve Degeneration |
| Inflammation Antibodies | >4 publications with PTPRZ and Inflammation |
| Vascular Diseases Antibodies | >4 publications with PTPRZ and Vascular Diseases |
| Skin Diseases Antibodies | >3 publications with PTPRZ and Skin Diseases |
| Breast Neoplasms Antibodies | >3 publications with PTPRZ and Breast Neoplasms |
| Necrosis Antibodies | >2 publications with PTPRZ and Necrosis |
| Lung Diseases Antibodies | >2 publications with PTPRZ and Lung Diseases |
Organs/Tissues associated with anti-PTPRZ antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >99 publications with PTPRZ and Brain |
| Embryonic Tissue Antibodies | >27 publications with PTPRZ and Embryonic Tissue |
| Spinal Cord Antibodies | >13 publications with PTPRZ and Spinal Cord |
| Eye Antibodies | >4 publications with PTPRZ and Eye |
| Lung Antibodies | >3 publications with PTPRZ and Lung |
| Artery Antibodies | >2 publications with PTPRZ and Artery |
| Testis Antibodies | >1 publications with PTPRZ and Testis |
| Bone Marrow Antibodies | >1 publications with PTPRZ and Bone Marrow |
| Intestine Antibodies | >1 publications with PTPRZ and Intestine |