Polyclonal Antibody to Syncoilin (SYNC)

Référence MBS2027327-0,2mL

Conditionnement : 0.2mL

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Syncoilin (SYNC) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2027327
SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2027327 is an antibody targeting SYNC. Also known as Polyclonal Antibody to Syncoilin (SYNC). Reactive in Human, Mouse, Rat, Pig, Bovine. Host: Rabbit. More details

Product Overview

Online Datasheet in PDF
Product Name
Syncoilin, Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Syncoilin (SYNC)
Product Gene Name
anti-SYNC antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Pig, Bovine
Form/Format
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
0.32mg/ml (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.

Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: SYNC (MBS2027327)
Immunogen: SYNC (MBS2031648)
Matching Pairs
Unconjugated Antibody: SYNC (MBS2027327)
APC-CY7 Conjugated Antibody: SYNC (MBS2077382)
OMIM
AK024707 mRNA
3D Structure
ModBase 3D Structure for Q9H7C4
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Polyclonal antibody preparation
Traits
Liquid
Cross Reactivity
Mouse
Immunogen
Recombinant SYNC (Ile169~Pro458) expressed in E.coli (MBS2031648).
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-SYNC antibody
Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP).
Application Notes for anti-SYNC antibody
Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-SYNC antibody

Western Blot:
Sample: Recombinant SYNC, Human.
Rabbit Anti-SYNC Polyclonal Antibody – Cat# MBS2027327

Western Blot (WB) of anti-SYNC antibody

Western Blot:
Sample: Lane1: Human Hela Cells;
Lane2: Mouse Heart Tissue.
Rabbit Anti-SYNC Polyclonal Antibody, Western Blot (WB) – Cat# MBS2027327

Immunohistochemistry (IHC) of anti-SYNC antibody

DAB staining on IHC-P. Samples: Human Tissue)
Rabbit Anti-SYNC Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2027327

Other Notes

Small volumes of anti-SYNC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SYNC. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
syncoilin isoform 2
NCBI Official Synonym Full Names
syncoilin, intermediate filament protein
NCBI Official Symbol
SYNC
NCBI Official Synonym Symbols
SYNC1; SYNCOILIN
UniProt Protein Name
Syncoilin
UniProt Synonym Protein Names
Syncoilin intermediate filament 1; Syncoilin-1
Protein Family
Syncoilin
UniProt Gene Name
SYNC
UniProt Synonym Gene Names
SYNC1
NCBI Protein Information
syncoilin

NCBI Summary for SYNC

This gene encodes a member of the intermediate filament family which contains an N-terminal head domain, followed by a central coiled-coil region and a short C-terminal tail. The protein is highly expressed in skeletal and cardiac muscle. The protein links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle and may have a structural role in striated muscle. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
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UniProt Comments for SYNC

SYNC1: a member of the intermediate filament family which contains an N-terminal head domain, followed by a central coiled-coil region and a short C-terminal tail. The protein is highly expressed in skeletal and cardiac muscle. The protein links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle and may have a structural role in striated muscle. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Chromosomal Location of Human Ortholog: 1p35.1

Cellular Component: cytosol; intermediate filament; neuromuscular junction; perinuclear region of cytoplasm; sarcolemma; Z disc

Molecular Function: structural molecule activity

Biological Process: intermediate filament-based process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SYNC antibody

 Reference Product  PubMed Publications
 DES antibody  >3 publications with SYNC and DES
 DMD antibody  >1 publications with SYNC and DMD

Diseases associated with anti-SYNC antibody

 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >16 publications with SYNC and Heart Diseases
 Breast Neoplasms Antibodies  >4 publications with SYNC and Breast Neoplasms
 Hemorrhage Antibodies  >3 publications with SYNC and Hemorrhage
 Fibrosis Antibodies  >3 publications with SYNC and Fibrosis
 Disease Models, Animal Antibodies  >3 publications with SYNC and Disease Models, Animal
 Inflammation Antibodies  >3 publications with SYNC and Inflammation
 Congenital Abnormalities Antibodies  >2 publications with SYNC and Congenital Abnormalities
 Lung Neoplasms Antibodies  >2 publications with SYNC and Lung Neoplasms
 Necrosis Antibodies  >2 publications with SYNC and Necrosis
 Hypertension Antibodies  >1 publications with SYNC and Hypertension

Organs/Tissues associated with anti-SYNC antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >64 publications with SYNC and Brain
 Heart Antibodies  >31 publications with SYNC and Heart
 Blood Antibodies  >25 publications with SYNC and Blood
 Muscle Antibodies  >21 publications with SYNC and Muscle
 Nerve Antibodies  >14 publications with SYNC and Nerve
 Eye Antibodies  >11 publications with SYNC and Eye
 Lung Antibodies  >11 publications with SYNC and Lung
 Bone Antibodies  >9 publications with SYNC and Bone
 Vascular Antibodies  >6 publications with SYNC and Vascular
 Connective Tissue Antibodies  >5 publications with SYNC and Connective Tissue