Quinacrine (dihydrochloride hydrate) [207671-43-0]
Référence T23210-1g
Conditionnement : 1g
Marque : TargetMol
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Quinacrine (dihydrochloride hydrate)
(Synonyms: Quinacrine hydrochloride hydrate (83-89-6 free base)) Copy Product InfoQuinacrine dihydrochloride hydrate possesses antiprotozoal and anti-infective properties and exhibits multi-target biological activity; it inhibits voltage-gated sodium channels (which are involved in the generation and conduction of action potentials) and aldehyde oxidase activity, and acts as a riboflavin antagonist to interfere with riboflavin-related protein interactions; Furthermore, quinacrine has been used in in vitro models to study the regulation of prion misfolding processes.
Cas No. 207671-43-0
For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Solid
Color:Yellow
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Quinacrine dihydrochloride hydrate possesses antiprotozoal and anti-infective properties and exhibits multi-target biological activity; it inhibits voltage-gated sodium channels (which are involved in the generation and conduction of action potentials) and aldehyde oxidase activity, and acts as a riboflavin antagonist to interfere with riboflavin-related protein interactions; Furthermore, quinacrine has been used in in vitro models to study the regulation of prion misfolding processes. |
| In vitro | Quinacrine dihydrochloride hydrate (0–20 μM, 24 h) inhibits the growth of SGC-7901 cells and induces apoptosis [3]. |
| In vivo | Quinacrine dihydrochloride hydrate (3–30 mg/kg, intraperitoneally, once daily for three consecutive days) exerts a protective effect against glycerol-induced acute kidney injury in rats [2]. |
| Synonyms | Quinacrine hydrochloride hydrate (83-89-6 free base) |
| Molecular Weight | 472.9 |
| Formula | C23H30ClN3O·2HCl·xH2O |
| Cas No. | 207671-43-0 |
| Smiles | ClC1=CC=C2C(NC(C)CCCN(CC)CC)=C3C(C=CC(OC)=C3)=NC2=C1.Cl.Cl.O |
| Relative Density. | no data available |
| Storage | Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | H2O: 9.33 mg/mL (19.73 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
H2O
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | |||||||||||||||||||||