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> Quinacrine mustard hydrochloride [4213-45-0]

Quinacrine mustard hydrochloride [4213-45-0]

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Référence T37031-10mg

Conditionnement : 10mg

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Quinacrine mustard hydrochloride

(Synonyms: Quinacrine mustard HCl) Copy Product Info
Quinacrine mustard hydrochloride is a fluorescent dye and polycyclic aromatic agent that acts as a mutagen to induce mutants in bacteria.Quinacrine mustard hydrochloride selectively binds to adenine-thymine (AT) base pairs, but not to guanine-cytosine (GC). Quinacrine mustard (hydrochloride) selectively binds to adenine-thymine (AT) base pairs rather than to guanine-cytosine (GC) base pairs, inducing cell cycle arrest at G2/M. Quinacrine mustard (hydrochloride) has been used to label chromosomes for karyotyping by autoradiography.
Quinacrine mustard hydrochloride
Cas No. 4213-45-0
For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Solid
Color:Yellow

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Product Introduction

Bioactivity
Description
Quinacrine mustard hydrochloride is a fluorescent dye and polycyclic aromatic agent that acts as a mutagen to induce mutants in bacteria.Quinacrine mustard hydrochloride selectively binds to adenine-thymine (AT) base pairs, but not to guanine-cytosine (GC). Quinacrine mustard (hydrochloride) selectively binds to adenine-thymine (AT) base pairs rather than to guanine-cytosine (GC) base pairs, inducing cell cycle arrest at G2/M. Quinacrine mustard (hydrochloride) has been used to label chromosomes for karyotyping by autoradiography.
In vitro
Quinacrine mustard hydrochloride (0.2 μM; 4h) induced cell cycle arrest at G2+M-phase with the accumulation of cells in this compartment by 50% in HL-60 cells.[1]
Quinacrine mustard hydrochloride (5 μg/ml) can be used for the DNA strain of plant, animal, or human chromosomes.[2]
Quinacrine mustard hydrochloride (28 μM) increases the number of mutants that appeared after exposure to bacteria.[3]
SynonymsQuinacrine mustard HCl
Cell Research
Cell experiment: Quinacrine mustard hydrochloride (0.2 μM; 4h) induced cell cycle arrest at the G2+M phase in HL-60 cells and increased the accumulation of cells in this phase by 50%.
Chemical Properties
Molecular Weight505.31
FormulaC23H29Cl4N3O
Cas No.4213-45-0
SmilesCl.ClC=1C=CC=2C(=NC=3C=CC(OC)=CC3C2NC(C)CCCN(CCCl)CCCl)C1
Relative Density.1.271g/cm3
Storage & Solubility Information
StorageStore at low temperature,Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Chloroform: Soluble
H2O: Soluble