RAB1A Antibody: ATTO 488
Référence MBS8005924-5x0,1mg
Conditionnement : 5x0.1mg
Marque : MyBiosource
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Western Blot analysis of Human, Mouse A549 WT and KO cells, MEF, mouse brain cells showing detection of RAB1A protein using Mouse Anti-RAB1A Monoclonal Antibody, Clone 4G10 . Lane 1: MW ladder. Lane 2: WT A549 cells. Lane 3-5: KO A549 clones. Lane 6: MEF cells. Lane 7: mouse brain cells.. Load: 10ug (A549, MEF); 20ug (Mouse Brain). Primary Antibody: Mouse Anti-RAB1A Monoclonal Antibody at 1:1000.
Immunoprecipitation analysis using Mouse Anti-RAB1A Monoclonal Antibody, Clone 4G10 . Tissue: HEK293 cells overexpressing RAB1A, RAB1B, and RAB1C. Species: Human. Primary Antibody: Mouse Anti-RAB1A Monoclonal Antibody .
RAB1A Antibody – Mouse Monoclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8005924Rab1A is mostly found in the membrane of the endoplasmic reticulum (ER) and Golgi apparatus and is involved in cell signaling, cancer, and neurodegenerative diseases (1). It regulates protein transport from the ER to the Golgi compartment and is involved in… More details
Product Overview
Online Datasheet in PDFProduct Name
RAB1A, Monoclonal Antibody
Full Product Name
RAB1A Antibody: ATTO 488
Product Gene Name
anti-RAB1A antibody
Product Synonym Names
Mouse Anti-Human RAB1A Monoclonal IgG1; RAB1A, Clone 4G10: ATTO 488; GTP binding protein RAB 1A antibody; antibody; RAB 1 antibody; Rab 1A antibody; Rab1A antibody; RAB1A member RAS oncogene family antibody; RAB1A_HUMAN antibody; Ras related protein Rab 1A antibody; Ras-related protein Rab-1A antibody; YPT1-related protein antibody; RAB1 Antibody
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4G10
Host
Mouse
Species Reactivity
Human, Mouse
Form/Format
PBS pH7.4, 50% glycerol, 0.09% Sodium Azide
Purity/Purification
Protein G Purified
Concentration
1mg/ml (lot specific)
Specificity
Detects ~23kDa. Cross-reacts with RAB1B and RAB1C.
Preparation and Storage
Store at -20 degree C
Shipping: Blue Ice
Shipping: Blue Ice
Molecular Weight
13,903 Da
OMIM
179508
Immunogen
Full length recombinant RAB1A protein
Immunogen Species
Human
Conjugation
ATTO 488
Tissue Specificity
Low tissue specificity.
Cellular Localization
Cytoplasm, Endoplasmic reticulum, Endosome, Golgi apparatus, Membrane
Product Categories/Family for anti-RAB1A antibody
Antibodies; Cancer; Cell Signaling; Cell Signaling; Autophagy| Golgi Proteins; Alzheimer's Disease; Growth Factors; Membrane Trafficking Proteins; Neurodegeneration; Neuroscience; Parkinson's Disease; Protein Trafficking
Applications Tested/Suitable for anti-RAB1A antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-RAB1A antibody
WB: 1:1000
A 1:1000 dilution was sufficient for detection of RAB1A in 10ug (A549, MEF); 20ug (Mouse Brain) lysates by ECL immunoblot analysis.
A 1:1000 dilution was sufficient for detection of RAB1A in 10ug (A549, MEF); 20ug (Mouse Brain) lysates by ECL immunoblot analysis.
Western Blot (WB) of anti-RAB1A antibody
Western Blot analysis of Human, Mouse A549 WT and KO cells, MEF, mouse brain cells showing detection of RAB1A protein using Mouse Anti-RAB1A Monoclonal Antibody, Clone 4G10 . Lane 1: MW ladder. Lane 2: WT A549 cells. Lane 3-5: KO A549 clones. Lane 6: MEF cells. Lane 7: mouse brain cells.. Load: 10ug (A549, MEF); 20ug (Mouse Brain). Primary Antibody: Mouse Anti-RAB1A Monoclonal Antibody at 1:1000.
Product References and Citations for anti-RAB1A antibody
1. Yang, X. et al. (2016) Oncogene. 35(44):5699-57042. pubchem.ncbi.nlm.nih.gov/protein/P62820
Other Notes
Small volumes of anti-RAB1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for RAB1A purchase
MBS8005924 is an antibody targeting RAB1A. Also known as RAB1A Antibody: ATTO 488. Reactive in Human, Mouse. Host: Mouse.
Additional Details
NCBI/Uniprot data below describe general gene information for RAB1A. It may not necessarily be applicable to this product.
NCBI Official Full Name
ras-related protein Rab-1A isoform 1
NCBI Official Synonym Full Names
RAB1A, member RAS oncogene family
NCBI Official Symbol
RAB1A
NCBI Official Synonym Symbols
RAB1; YPT1
UniProt Protein Name
Ras-related protein Rab-1A
UniProt Synonym Protein Names
YPT1-related protein
Protein Family
Ras-related protein
UniProt Gene Name
RAB1A
UniProt Synonym Gene Names
RAB1
UniProt Entry Name
RAB1A_HUMAN
NCBI Protein Information
ras-related protein Rab-1A; GTP binding protein Rab1a; RAB1, member RAS oncogene family; Rab GTPase YPT1 homolog; YPT1-related protein
NCBI Summary for RAB1A
This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. [provided by RefSeq, Oct 2008]
Show more UniProt Comments for RAB1A
RAB1A: Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity. Belongs to the small GTPase superfamily. Rab family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: G protein, monomeric; G protein, monomeric, Rab; G protein
Chromosomal Location of Human Ortholog: 2p14
Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; early endosome; melanosome; cytosol
Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding
Biological Process: ER to Golgi vesicle-mediated transport; cell migration; endocytosis; virus assembly; melanosome transport; vesicle-mediated transport; growth hormone secretion; intracellular protein transport; defense response to bacterium; vesicle transport along microtubule; autophagy; cilium biogenesis; mitotic cell cycle; Rab protein signal transduction; Golgi organization and biogenesis; autophagic vacuole formation
Show more Protein type: G protein, monomeric; G protein, monomeric, Rab; G protein
Chromosomal Location of Human Ortholog: 2p14
Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; early endosome; melanosome; cytosol
Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding
Biological Process: ER to Golgi vesicle-mediated transport; cell migration; endocytosis; virus assembly; melanosome transport; vesicle-mediated transport; growth hormone secretion; intracellular protein transport; defense response to bacterium; vesicle transport along microtubule; autophagy; cilium biogenesis; mitotic cell cycle; Rab protein signal transduction; Golgi organization and biogenesis; autophagic vacuole formation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-RAB1A antibody
| Reference Product | PubMed Publications |
|---|---|
| RUSC2 antibody | >2 publications with RAB1A and RUSC2 |
| CHML antibody | >1 publications with RAB1A and CHML |
Pathways associated with anti-RAB1A antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Cell Cycle Pathway antibodies | Cell Cycle Pathway Diagram |
| Cell Cycle, Mitotic Pathway antibodies | Cell Cycle, Mitotic Pathway Diagram |
| Golgi Cisternae Pericentriolar Stack Reorganization Pathway antibodies | Golgi Cisternae Pericentriolar Stack Reorganization Pathway Diagram |
| Legionellosis Pathway antibodies | Legionellosis Pathway Diagram |
| Legionellosis Pathway antibodies | Legionellosis Pathway Diagram |
| M Phase Pathway antibodies | M Phase Pathway Diagram |
| Mitotic Prophase Pathway antibodies | Mitotic Prophase Pathway Diagram |
| PLK1 Signaling Events Pathway antibodies | PLK1 Signaling Events Pathway Diagram |
Diseases associated with anti-RAB1A antibody
| Disease Name | Pubmed Publications |
|---|---|
| Carcinoma, Squamous Cell Antibodies | >3 publications with RAB1A and Carcinoma, Squamous Cell |
| Neoplasm Invasiveness Antibodies | >2 publications with RAB1A and Neoplasm Invasiveness |
| Fibrosis Antibodies | >2 publications with RAB1A and Fibrosis |
| Intestinal Neoplasms Antibodies | >2 publications with RAB1A and Intestinal Neoplasms |
| Cardiomyopathies Antibodies | >1 publications with RAB1A and Cardiomyopathies |
| Precancerous Conditions Antibodies | >1 publications with RAB1A and Precancerous Conditions |
| Hypertrophy Antibodies | >1 publications with RAB1A and Hypertrophy |
Organs/Tissues associated with anti-RAB1A antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Nerve Antibodies | >7 publications with RAB1A and Nerve |
| Muscle Antibodies | >6 publications with RAB1A and Muscle |
| Brain Antibodies | >6 publications with RAB1A and Brain |
| Heart Antibodies | >4 publications with RAB1A and Heart |
| Kidney Antibodies | >3 publications with RAB1A and Kidney |
| Pancreas Antibodies | >3 publications with RAB1A and Pancreas |
| Eye Antibodies | >3 publications with RAB1A and Eye |
| Mouth Antibodies | >3 publications with RAB1A and Mouth |
| Bone Antibodies | >3 publications with RAB1A and Bone |
| Liver Antibodies | >3 publications with RAB1A and Liver |