250721 | Rabbit Anti-Insulin Receptor Polyclonal Antibody Biovalley

Rabbit Polyclonal Antibody

Cat. No.

250721

Unit

0.1 mg

Description

INSR binds insulin and has a tyrosine protein kinase activity. The short isoform has a higher affinity for insulin. The receptor mediates the metabolic functions of insulin. The receptor binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Defects in INSR are the cause of insulin resistance. This antibody is against the alpha subunit.

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Datasheet

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Isotype

Rabbit Ig

Applications

IHC

Species Reactivity

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Alternate Names

Insulin receptor; CD220 antigen; IR; INSR

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Accession No.

P06213

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human INSR-alpha.

Application Notes

E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Images

Insulin receptor staining in rat liver. Formalin-fixed paraffin-embedded rat liver tissue is stained with Insulin Receptor Antibody (Cat. No. 250721) used at 1:200 dilution.

For research use only, not for diagnostic or therapeutic procedures.

Rabbit Anti-Insulin Receptor Polyclonal Antibody

Référence 250721

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Marque : Abbiotec

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