rbcL Antibody
Référence OACA00109
Conditionnement : 100ug
Marque : Aviva Systems Biology
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ILK Recombinant Antibody [6A5] (OACA12854)
| Datasheets/Manuals | Printable datasheet for ILK Recombinant Antibody [6A5] (OACA12854) |
|---|
| Predicted Species Reactivity | Human|Mouse |
|---|---|
| Product Format | Liquid |
| Clonality | Recombinant Monoclonal |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay, Immunofluorescence, Immunoprecipitation, Western blot |
| Reconstitution and Storage | -20°C or -80°C |
| Immunogen | A synthesized peptide derived from human ILK |
| Purification | Affinity Purified |
| Gene Symbol | ILK |
|---|---|
| Gene Full Name | integrin linked kinase |
| Alias Symbols | 59 kDa serine/threonine-protein kinase;beta-integrin-linked kinase;epididymis secretory protein Li 28;HEL-S-28;ILK-1;ILK-2;integrin-linked kinase-2;integrin-linked protein kinase;P59;p59ILK. |
| NCBI Gene Id | 3611 |
| Protein Name | Integrin-linked protein kinase |
| Description of Target | Receptor-proximal protein kinase regulating integrin-mediated signal transduction (PubMed:8538749, PubMed:9736715). May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B (PubMed:8538749, PubMed:9736715). |
| Uniprot ID | Q13418 |