RCHY1 Antibody - N-terminal region - HRP
Référence ARP42973_P050-HRP
Conditionnement : 100ul
Marque : Aviva Systems Biology
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RCHY1 Antibody - N-terminal region : HRP (ARP42973_P050-HRP)
| Datasheets/Manuals | Printable datasheet for anti-RCHY1 (ARP42973_P050-HRP) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human RCHY1 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 100%; Rat: 100%; Sheep: 100% |
| Peptide Sequence | Synthetic peptide located within the following region: KLYTCRLCHDNNEDHQLDRFKVKEVQCINCEKIQHAQQTCEECSTLFGEY |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-RCHY1 (ARP42973_P050-HRP) antibody is Catalog # AAP42973 (Previous Catalog # AAPS13411) |
| Sample Type Confirmation | RCHY1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
| Reference | Maruyama,S., Mol. Cell. Biochem. 307 (1-2), 73-82 (2008) |
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| Gene Symbol | RCHY1 |
| Gene Full Name | Ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
| Alias Symbols | ZCHY, ARNIP, CHIMP, PIRH2, RNF199, ZNF363, PRO1996 |
| NCBI Gene Id | 25898 |
| Protein Name | RING finger and CHY zinc finger domain-containing protein 1 |
| Description of Target | RCHY1 has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53.The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Uniprot ID | Q96PM5 |
| Protein Accession # | NP_001008925 |
| Nucleotide Accession # | NM_001008925 |
| Protein Size (# AA) | 200 |
| Molecular Weight | 23kDa |
| Protein Interactions | MEOX2; NOTCH2NL; UBASH3B; KRTAP9-2; LIMS2; SEMA4C; WDR74; ADAMTSL4; RCHY1; PGLS; KLHL41; MDM2; TAOK2; TP53; UBC; RNF2; HOXA2; YWHAE; CDK9; DCUN1D5; RILP; TMBIM1; CHD8; USP28; C19orf80; RBM38; NLK; TMEM14C; AIG1; SERTAD1; CHEK2; PRDX4; RAB11A; FADS6; TMEM1 |
