Recombinant Bordetella pertussis Pertussis toxin subunit 1

Référence MBS9420997-0,1mg

Conditionnement : 0.1mg

Marque : MyBiosource

Contactez votre distributeur local :


Téléphone : +1 850 650 7790

Pertussis Toxin Subunit 1 (TOX1) BORPE Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9420997

S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G… More details

Product Overview

Online Datasheet in PDF
Product Name
Pertussis toxin subunit 1 (TOX1), Recombinant Protein
Full Product Name
Recombinant Bordetella pertussis Pertussis toxin subunit 1
Product Gene Name
TOX1 recombinant protein
Product Synonym Names
Islet-activating protein S1; IAP S1NAD-dependent ADP-ribosyltransferase (EC:2.4.2.-)
Host
E Coli
Species Reactivity
BORPE
Form/Format
20mM Tris-HCl based buffer, pH8.0
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Molecular Weight
30.3kD
Sequence Positions
Full Length, 35-269aa
3D Structure
ModBase 3D Structure for P04977
Tag Info
His-tag

Other Notes

Small volumes of TOX1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TOX1 purchase

MBS9420997 is a recombinant protein targeting TOX1. Also known as Recombinant Bordetella pertussis Pertussis toxin subunit 1. Reactive in BORPE. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TOX1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
pertussis toxin subunit 1
NCBI Official Symbol
ptxA
UniProt Protein Name
Pertussis toxin subunit 1
UniProt Synonym Protein Names
Islet-activating protein S1; IAP S1; NAD-dependent ADP-ribosyltransferase (EC:2.4.2.-)
Protein Family
Pertussis toxin
UniProt Gene Name
ptxA
UniProt Synonym Gene Names
PTX S1; IAP S1
NCBI Protein Information
pertussis toxin subunit 1

UniProt Comments for TOX1

S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD+ into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TOX1 recombinant protein

 Reference Product  PubMed Publications
 prn recombinant protein  >13 publications with TOX1 and prn
 fim3 recombinant protein  >11 publications with TOX1 and fim3
 fhaB recombinant protein  >5 publications with TOX1 and fhaB
 ptxC recombinant protein  >5 publications with TOX1 and ptxC
 ptxB recombinant protein  >1 publications with TOX1 and ptxB

Pathways associated with TOX1 recombinant protein

 Products by Pathway  Pathway Diagram
 Pertussis Pathway antibodies  Pertussis Pathway Diagram
 Pertussis Pathway antibodies  Pertussis Pathway Diagram
 Pertussis Pathogenicity Signature 1, Pertussis Toxin Pathway antibodies  Pertussis Pathogenicity Signature 1, Pertussis Toxin Pathway Diagram
 Pertussis Pathogenicity Signature 1, Pertussis Toxin Pathway antibodies  Pertussis Pathogenicity Signature 1, Pertussis Toxin Pathway Diagram