Recombinant Histone H4 (H4)
Référence MBS2097677-0,01mg
Conditionnement : 0.01mg
Marque : MyBiosource
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Histone H4 (H4) Homo Sapiens (Human) Recombinant Protein
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2097677SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2097677 is a recombinant protein targeting H4. Also known as Recombinant Histone H4 (H4). Reactive in Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat), Cavia (Guinea pig ), Rhesus monkey (Simian), Felis catus; Feline (Cat), Canis… More details
Product Overview
Online Datasheet in PDFProduct Name
Histone H4 (H4), Recombinant Protein
Full Product Name
Recombinant Histone H4 (H4)
Product Gene Name
H4 recombinant protein
Host
E.coli
Species Reactivity
Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat), Cavia (Guinea pig ), Rhesus monkey (Simian), Felis catus; Feline (Cat), Canis familiaris; Canine (Dog), Sus scrofa; Porcine (Pig), Bos taurus; Bovine (Cattle), Equus caballus; Equine (Ho
Form/Format
20mM Tris, 150mM NaCl, pH8.0, containing 0.01% skl, 5%Trehalose.
Purity/Purification
> 90%
Concentration
Original Concentration: 50ug/mL (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 2-8 degree C for one month.
Aliquot and store at -80 degree C for 12 months.
Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Avoid repeated freeze/thaw cycles.
Store at 2-8 degree C for one month.
Aliquot and store at -80 degree C for 12 months.
Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Molecular Weight
Predicted Molecular Mass: 41.3kDa
Accurate Molecular Mass: 42kDa as determined by SDS-PAGE reducing conditions.
Accurate Molecular Mass: 42kDa as determined by SDS-PAGE reducing conditions.
OMIM
X00038 Genomic DNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Prokaryotic expression
Residues
Ser2~Gly103
Tags
N-terminal His and GST Tag
Subcellular Location
Secreted, Chromosome
Traits
Freeze-dried powder
Predicted isoelectric point
11.9
Usage
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
Product Categories/Family for H4 recombinant protein
Signal transduction; Developmental science
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for H4 recombinant protein
Positive Control; Immunogen; SDS-PAGE; Western Blot (WB).
Application Notes for H4 recombinant protein
(May be suitable for use in other assays to be determined by the end user.)
Other Notes
Small volumes of H4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for H4. It may not necessarily be applicable to this product.
NCBI Official Full Name
histone H4
NCBI Official Synonym Full Names
histone cluster 2 H4 family member a
NCBI Official Symbol
HIST2H4A
NCBI Official Synonym Symbols
H4; H4/n; H4F2; H4FN; FO108; HIST2H4
UniProt Protein Name
Histone H4
Protein Family
Antigen
UniProt Gene Name
HIST1H4A
UniProt Synonym Gene Names
H4/A; H4FA
NCBI Protein Information
histone H4
NCBI Summary for H4
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. [provided by RefSeq, Aug 2015]
Show more UniProt Comments for H4
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Show more Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with H4 recombinant protein
| Products by Pathway | Pathway Diagram |
|---|---|
| Alcoholism Pathway antibodies | Alcoholism Pathway Diagram |
| Alcoholism Pathway antibodies | Alcoholism Pathway Diagram |
| Amyloids Pathway antibodies | Amyloids Pathway Diagram |
| Cell Cycle Pathway antibodies | Cell Cycle Pathway Diagram |
| Chromosome Maintenance Pathway antibodies | Chromosome Maintenance Pathway Diagram |
| Deposition Of New CENPA-containing Nucleosomes At The Centromere Pathway antibodies | Deposition Of New CENPA-containing Nucleosomes At The Centromere Pathway Diagram |
| Disease Pathway antibodies | Disease Pathway Diagram |
| Gastric Cancer Network 1 Pathway antibodies | Gastric Cancer Network 1 Pathway Diagram |
| Gene Expression Pathway antibodies | Gene Expression Pathway Diagram |
| Meiosis Pathway antibodies | Meiosis Pathway Diagram |