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> Recombinant human Glucagon-like peptide 1 receptor

Recombinant human Glucagon-like peptide 1 receptor

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Référence OPCA00101-1MG

Conditionnement : 1mg

Marque : Aviva Systems Biology

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GLP1R Recombinant Protein (Human) (OPCA00101)

GLP1R Recombinant Protein (Human) (OPCA00101)
Datasheets/ManualsPrintable datasheet for GLP1R Recombinant Protein (Human) (OPCA00101)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatLiquid or Lyophilized powder
Additional Information Tag information : His tag
Reconstitution and Storage-20°C or -80°C
PurityGreater than 90% as determined by SDS-PAGE.
Peptide SequenceRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLY
Protein SequenceRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLY
Storage BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
SourceE.coli
Protein Range24-145 aa
TagN-terminal 6xHis-tagged
ReferenceRegulation of GIP and GLP1 receptor cell surface expression by N-glycosylation and receptor heteromerization.Whitaker G.M., Lynn F.C., McIntosh C.H., Accili E.A.PLoS ONE 7:E32675-E32675(2012)
Gene SymbolGLP1R
Gene Full Nameglucagon like peptide 1 receptor
Alias SymbolsGLP-1, GLP-1 receptor, GLP-1-R, GLP-1R, GLP1 receptor, glucagon-like peptide 1 receptor, seven transmembrane helix receptor.
NCBI Gene Id2740
Protein NameGlucagon-like peptide 1 receptor
Description of TargetG-protein coupled receptor for glucagon-like peptide 1 (GLP-1) (PubMed:8405712, PubMed:8216285, PubMed:7517895, PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels (PubMed:8405712, PubMed:8216285, PubMed:7517895, PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449). Plays a role in regulating insulin secretion in response to GLP-1 (By similarity).
Uniprot IDP43220
Protein Size (# AA)Partial
Molecular Weight18.3 kDa