Recombinant Human MLN Protein

Référence MBS8249453-0,05mg

Conditionnement : 0.05mg

Marque : MyBiosource

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MLN Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8249453

Recombinant Human MLN Protein is produced by our mammalian expression system and the target gene encoding Phe26-Lys115 is expressed with a 6His tag at the C-terminus. More details

Product Overview

Online Datasheet in PDF
Product Name
MLN, Recombinant Protein
Full Product Name
Recombinant Human MLN Protein
Product Gene Name
MLN recombinant protein
Product Synonym Names
Promotilin
Sequence
FVPIFTYGEL QRMQEKERNK GQKKSLSVWQ RSGEEGPVDP AEPIREEENE MIKLTAPLEI GMRMNSRQLE KYPATLEGLL SEMLPQHAAK VDHHHHHH
Host
Human cells
Species Reactivity
Human
Form/Format
Lyophilized from a 0.2 muM filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Purity/Purification
Greater than 95% as determined by reducing SDS-PAGE.
Preparation and Storage
Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.
Molecular Weight
12,849 Da
OMIM
Y00695 mRNA
3D Structure
ModBase 3D Structure for P12872
Endotoxin
Less than 0.1 ng/mug (1 IEU/mug) as determined by LAL test.
Directions for Use
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 mug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Applications Tested/Suitable for MLN recombinant protein
ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)

Other Notes

Small volumes of MLN recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MLN purchase

MBS8249453 is a recombinant protein targeting MLN. Also known as Recombinant Human MLN Protein. Reactive in Human. Host: Human cells.

Additional Details

NCBI/Uniprot data below describe general gene information for MLN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
promotilin isoform 2 preproprotein
NCBI Official Synonym Full Names
motilin
NCBI Official Symbol
MLN
UniProt Protein Name
Promotilin
Protein Family
Motilin
UniProt Gene Name
MLN
UniProt Synonym Gene Names
MAP
UniProt Entry Name
MOTI_HUMAN
NCBI Protein Information
promotilin

NCBI Summary for MLN

This gene encodes a small peptide hormone that is secreted by cells of the small intestine to regulate gastrointestinal contractions and motility. Proteolytic processing of the secreted protein produces the mature peptide and a byproduct referred to as motilin-associated peptide (MAP). Three transcript variants encoding different preproprotein isoforms but the same mature peptide have been found for this gene. [provided by RefSeq, May 2010]
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UniProt Comments for MLN

MLN: Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle. Belongs to the motilin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: extracellular region

Molecular Function: receptor binding

Biological Process: cell-cell signaling; G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MLN recombinant protein

 Reference Product  PubMed Publications
 NTS recombinant protein  >4 publications with MLN and NTS
 MLNR recombinant protein  >3 publications with MLN and MLNR
 GRP recombinant protein  >1 publications with MLN and GRP
 TAC1 recombinant protein  >1 publications with MLN and TAC1
 GCG recombinant protein  >1 publications with MLN and GCG

Pathways associated with MLN recombinant protein

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram

Diseases associated with MLN recombinant protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >266 publications with MLN and Inflammation
 Disease Models, Animal Antibodies  >202 publications with MLN and Disease Models, Animal
 Necrosis Antibodies  >115 publications with MLN and Necrosis
 Kidney Diseases Antibodies  >51 publications with MLN and Kidney Diseases
 Weight Loss Antibodies  >31 publications with MLN and Weight Loss
 Neoplasms, Experimental Antibodies  >29 publications with MLN and Neoplasms, Experimental
 Hypertension Antibodies  >28 publications with MLN and Hypertension
 Breast Neoplasms Antibodies  >21 publications with MLN and Breast Neoplasms
 Drug Hypersensitivity Antibodies  >18 publications with MLN and Drug Hypersensitivity
 Hyperplasia Antibodies  >15 publications with MLN and Hyperplasia

Organs/Tissues associated with MLN recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Stomach Antibodies  >40 publications with MLN and Stomach