SB431542

Référence MBS808210-5x25mg

Conditionnement : 5x25mg

Marque : MyBiosource

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SB431542 Small Molecule

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS808210

SB431542 is a potent and selective inhibitor of the transforming growth factor-beta (TGF-beta) type I receptor, activin receptor-like kinases. It has been shown to inhibit ALK4, 5, and 7. More details

Product Overview

Product Name
SB431542, Small Molecule
Full Product Name
SB431542
Product Gene Name
SB431542 small molecule
Product Synonym Names
ALK4,5 and 7 kinase inhibitor; SB 431542; 4-(5-Benzol[1,3]dioxol-5-yl-4-pyrldin-2-yl-1H-imidazol-2-yl)-benzamide hydrate; 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide hydrate; 4-[4-(3,4-Methylenedioxyphenyl)-5-(2-pyridyl)-1H-imidazol-2-yl]-benzamide hydrate
Host
Synthetic
Form/Format
Yellow solid
Purity/Purification
>=98% (HPLC)
Preparation and Storage
Ships on blue ice. Store at 4°C.
Molecular Weight
384.4
Solubility
Soluble to 10 mM in ethanol and to 100 mM in DMSO
CAS Number
301836-41-9
Molecular Formula
C22H16N4O3
SMILES
C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5
Research
Cell Signaling

Chemical Structure of SB431542 small molecule

Chemical structure of SB431542 (SIH-511), a ALK4,5 and 7 kinase inhibitor. CAS #: 301836-41-9. Molecular Formula: C22H16N4O3. Molecular Weight: 384.4 g/mol.
SB431542 Small Molecule – Cat# MBS808210

Product References and Citations for SB431542 small molecule

1. Laping N.J., et al. (2002) Mol. Pharm. 62(1): 58-64.

Other Notes

Small volumes of SB431542 small molecule vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SB431542 purchase

MBS808210 is a small molecule targeting SB431542. Host: Synthetic.