SIX2 Antibody
Référence MBS8516981-0,1mL-AF647
Conditionnement : 0.1mL(AF647)
Marque : MyBiosource
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Western blot analysis SIX2 using HUVEC whole cell lysates
SIX2 Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8516981The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain.Six2, Six4 (AREC3) and Six5 bind to the same DNA sequence,indicating that they may regulate the same target genes. Six1 and Six4 are… More details
Product Overview
Online Datasheet in PDFProduct Name
SIX2, Polyclonal Antibody
Full Product Name
SIX2 Antibody
Product Gene Name
anti-SIX2 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
(Predicted: Human, Mouse,Rat, Sheep, Cow, Dog, Horse)
Form/Format
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol
Purity/Purification
Affinity purified by Protein A
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Application Notes for anti-SIX2 antibody
WB (1:500-2000), IHC-P (1:100-500), IHC-F (1:100-500), IF (1:100-500), ICC/IF (1:100-500), ELISA (1:5000-10000)
Other Notes
Small volumes of anti-SIX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for SIX2 purchase
MBS8516981 is an antibody targeting SIX2. Also known as SIX2 Antibody. Reactive in (Predicted: Human, Mouse,Rat, Sheep, Cow, Dog, Horse). Host: Rabbit.
Additional Details
NCBI/Uniprot data below describe general gene information for SIX2. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
integrin alpha-X isoform 2
NCBI Official Synonym Full Names
integrin subunit alpha X
NCBI Official Symbol
ITGAX
NCBI Official Synonym Symbols
CD11C; SLEB6
UniProt Protein Name
Integrin alpha-X
UniProt Synonym Protein Names
CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD_antigen: CD11c
Protein Family
Homeobox protein
UniProt Gene Name
ITGAX
UniProt Synonym Gene Names
CD11C
NCBI Protein Information
integrin alpha-X
NCBI Summary for SIX2
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Show more UniProt Comments for SIX2
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-SIX2 antibody
| Reference Product | PubMed Publications |
|---|---|
| ITGAM antibody | >924 publications with SIX2 and ITGAM |
| ITGB2 antibody | >397 publications with SIX2 and ITGB2 |
| ICAM1 antibody | >136 publications with SIX2 and ICAM1 |
| FGG antibody | >2 publications with SIX2 and FGG |
Pathways associated with anti-SIX2 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Cell Surface Interactions At The Vascular Wall Pathway antibodies | Cell Surface Interactions At The Vascular Wall Pathway Diagram |
| ECM Proteoglycans Pathway antibodies | ECM Proteoglycans Pathway Diagram |
| Extracellular Matrix Organization Pathway antibodies | Extracellular Matrix Organization Pathway Diagram |
| Focal Adhesion Pathway antibodies | Focal Adhesion Pathway Diagram |
| Hemostasis Pathway antibodies | Hemostasis Pathway Diagram |
| Integrin Cell Surface Interactions Pathway antibodies | Integrin Cell Surface Interactions Pathway Diagram |
| Integrin-mediated Cell Adhesion Pathway antibodies | Integrin-mediated Cell Adhesion Pathway Diagram |
| Regulation Of Actin Cytoskeleton Pathway antibodies | Regulation Of Actin Cytoskeleton Pathway Diagram |
| Regulation Of Actin Cytoskeleton Pathway antibodies | Regulation Of Actin Cytoskeleton Pathway Diagram |
| Signal Transduction Pathway antibodies | Signal Transduction Pathway Diagram |
Diseases associated with anti-SIX2 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Neoplasms Antibodies | >551 publications with SIX2 and Neoplasms |
| Inflammation Antibodies | >447 publications with SIX2 and Inflammation |
| Necrosis Antibodies | >330 publications with SIX2 and Necrosis |
| Disease Models, Animal Antibodies | >259 publications with SIX2 and Disease Models, Animal |
| Nervous System Diseases Antibodies | >105 publications with SIX2 and Nervous System Diseases |
| Neoplasms, Experimental Antibodies | >101 publications with SIX2 and Neoplasms, Experimental |
| Cardiovascular Diseases Antibodies | >91 publications with SIX2 and Cardiovascular Diseases |
| Leukemia, Myeloid, Acute Antibodies | >72 publications with SIX2 and Leukemia, Myeloid, Acute |
| Asthma Antibodies | >66 publications with SIX2 and Asthma |
| Liver Diseases Antibodies | >52 publications with SIX2 and Liver Diseases |
Organs/Tissues associated with anti-SIX2 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >2011 publications with SIX2 and Blood |
| Bone Marrow Antibodies | >502 publications with SIX2 and Bone Marrow |
| Spleen Antibodies | >420 publications with SIX2 and Spleen |
| Lymph Node Antibodies | >370 publications with SIX2 and Lymph Node |
| Lung Antibodies | >266 publications with SIX2 and Lung |
| Intestine Antibodies | >116 publications with SIX2 and Intestine |
| Brain Antibodies | >88 publications with SIX2 and Brain |
| Thymus Antibodies | >75 publications with SIX2 and Thymus |
| Eye Antibodies | >57 publications with SIX2 and Eye |
| Kidney Antibodies | >48 publications with SIX2 and Kidney |