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> SLC9A1 Rabbit Polyclonal Antibody

SLC9A1 Rabbit Polyclonal Antibody

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Référence TA306493

Conditionnement : 100ug

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SLC9A1 Rabbit Polyclonal Antibody

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SKU
TA306493
Rabbit Polyclonal Nhe-1 Antibody
Size:
100 ug
Conjugation:
Unconjugated
 

View other "SLC9A1 or NM_003047" antibodies

Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Nhe-1 antibody was raised against a 17 amino acid synthetic peptide near the center of the human Nhe-1. The immunogen is located within amino acids 490 - 540 of Nhe-1.
Buffer PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification Affinity chromatography purified via peptide column
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name solute carrier family 9 member A1
Database Link
Background The Na+/H+ antiporter (Nhe-1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells and is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, and tumor promoters. Nhe-1 acts as an anchor for actin filaments to control the integrity of the cortical cytoskeleton. This occurs through a previously unrecognized structural link between Nhe-1 and the actin-binding proteins ezrin, radixin, and moesin, collectively referred to as ERM proteins. A structural role for Nhe-1 has been proposed in regulating the cortical cytoskeleton that is independent of its function as an ion exchanger. It is also thought that Nhe-1 play a role in hypertension. At least two isoforms of Nhe-1 are known to exist.
Synonyms APNH; NHE-1; NHE1; PPP1R143
Reference Data
Protein Categories Membrane Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cardiac muscle contraction, Regulation of actin cytoskeleton
Product Manuals
FAQs
  • Antibody and Western Standard
SDS

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